29378-60-7

Upstream product

• 56962-67-5 3-nitro-4-(2-pyridylamino)coumarin 
• 627-13-4 propyl nitrate 
• 118-93-4 o-hydroxyacetophenone 
• 20261-31-8 4-hydroxy-3-nitrocoumarin 

Downstream Products

• 10524-88-6 3-Nitro-2-phenyl-4H-benzopyran-4-one 
• 1363156-60-8 C₁₆H₁₁NO₄ 
• 1363156-98-2 2-(3-amino-7-(dimethylamino)quinolin-2-yl)phenol 
• 1363156-97-1 2-(3-amino-6,7-dimethoxyquinolin-2-yl)phenol 
• 1363156-96-0 2-(3-amino-5,7-dimethoxyquinolin-2-yl)phenol 
• 1363156-93-7 6-amino-7-(2-hydroxyphenyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 1363156-92-6 6-amino-7-(2-hydroxyphenyl)-1-methylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 1363156-91-5 6-amino-7-(2-hydroxyphenyl)-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione 
• 1363156-89-1 5-amino-6-(2-hydroxyphenyl)-1-methyl-1,2-dihydropyrazolo[3,4-b]pyridin-3-one 
• 1363156-88-0 5-amino-6-(2-hydroxyphenyl)-2-methyl-1,2-dihydropyrazolo[3,4-b]pyridin-3-one 
• 1363156-87-9 5-amino-6-(2-hydroxyphenyl)-2-phenyl-1,2-dihydropyrazolo[3,4-b]pyridin-3-one 
• 1363156-86-8 5-amino-1-cyclohexyl-6-(2-hydroxyphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile 
• 1363156-85-7 5-amino-1-(4-methoxybenzyl)-6-(2-hydroxyphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile 
• 1363156-84-6 5-amino-1-tert-butyl-6-(2-hydroxyphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile 

Relevant academic research and scientific papers

Synthesis and reactions of some 4-heteroaryl-3-nitrocoumarins

By the action of 2-aminothiazole, 2-aminopyridines, and 2-aminopyrimidines, respectively, on 4-chloro-3-nitrocoumarin (3) the corresponding 4-heteroarylamino-3-nitrocoumarins 5-7 have been isolated in very good yields. Reactions of coumarins 6 and 7 with either aqueous tetrabutylammonium bisulfate/sodium hydroxide in a two phase system or 5% aqueous sodium hydroxide have been studied.

Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells

The implication of DNA methylation in cancer is today clearly established. Despite that nucleoside analogues are currently used for leukaemia treatment, their low stability in physiological conditions and their lack of selectivity arise the need for the i

Synthesis of heteroannulated 3-nitro- and 3-aminopyridines by cyclocondensation of electron-rich aminoheterocycles with 3-nitrochromone

3-Nitrochromone reacts with electron-rich aminoheterocycles (in glacial acetic acid at reflux) and anilines (in a mixture of DMF and TMSCl at 100-140 °C) to give a variety of hetero(carbo)annulated 3-nitropyridines. The reaction, involving a formal [3+3] cyclocondensation, proceeds in high yields and appears not to be influences greatly by the nature of the 1,3-C,N-dinucleophile as seen from the thorough scope study. The synthetic utility of the products was demonstrated by their conversion into the corresponding 3-aminopyridine derivatives. An NMR study and X-ray crystallographic analysis are reported.