29417-79-6Relevant academic research and scientific papers
C?Boron Enolates Enable Palladium Catalyzed Carboboration of Internal 1,3-Enynes
Chrostowska, Anna,Lamine, Walid,Li, Bo,Liu, Shih-Yuan,Miqueu, Karinne,Sotiropoulos, Jean-Marc,Wang, Ziyong,Wu, Jason
supporting information, p. 21231 - 21236 (2021/09/02)
A new family of carbon-bound boron enolates, generated by a kinetically controlled halogen exchange between chlorocatecholborane and silylketene acetals, is described. These C?boron enolates are demonstrated to activate 1,3-enyne substrates in the presence of a Pd0/Senphos ligand complex, resulting in the first examples of a carboboration reaction of an alkyne with enolate-equivalent nucleophiles. Highly substituted dienyl boron building blocks are produced in excellent site-, regio-, and diastereoselectivity by the described catalytic cis-carboboration reaction.
Preparation method for indanone compound
-
Paragraph 0092-0094, (2018/08/28)
The invention especially relates to a preparation method for an indanone compound, belonging to the field of organic synthesis. The preparation method for the indanone compounds comprises the following steps: 1) subjecting a compound as shown in a formula I and a compound as shown in a formula II to a condensation reaction so as to prepare a compound as shown in a formula III; 2) subjecting the compound as shown in the formula III to hydrolysis in the presence of alkali so as to prepare a compound as shown in a formula IV; and 3) carrying out acylation and ring closure on the compound as shownin the formula IV so as to prepare the as shown in a formula V. Compared with the prior art, the preparation method for the indanone compound in the invention has the advantages of low raw material cost, simple operation, low production of waste water, waste gas and industrial residues, high yield and the like, and is more suitable for industrial production; and compared with various traditionalpreparation methods for the indanone compound, the preparation method of the invention has obvious advantages and shows good industrialization prospects.
Sm/HOAc/EtOH system-mediated reduction of Baylis-Hillman acetates
Liu, Yunkui,Mao, Dajie,Xu, Danqian,Xu, Zhenyuan,Zhang, Yongmin
, p. 4389 - 4397 (2008/03/14)
Selective formation of (2E)-2-methylalk-2-enoates or 2-methyl alkanoates could be achieved in moderate to good yields under mild conditions via Sm/HOAc/EtOH system-mediated reduction of Baylis-Hillman acetates depending on the amount of samarium consumed in the reactions. Copyright Taylor & Francis Group, LLC.
Free-Radical Coupling of Alkyl and Aryl Halides with Electron-Deficient Alkenes Mediated by Chromium(II) Complexes
Tashtoush, Hasan I.,Sustmann, Reiner
, p. 1759 - 1762 (2007/10/02)
Free radicals generated from organic halides and (ethylenediamine)chromium(II) complexes in DMF are trapped by electron-deficient olefins.The coupling reactions of alkyl halides, described in Part I, are extended and, in addition, aryl halides are shown to be efficient radical precursors to yield coupling products in good yield. Key Words: Bond formation, C-C/ Chromium(II) complexes/ Radicals
