29418-16-4Relevant academic research and scientific papers
Iodine-Mediated Cross-Dehydrogenative Coupling of Heterocyclic Thiols with Amines: An Easy and Practical Formation of S?N Bond
Dong, Zhi-Bing,Fan, Yong-Hao,Hao, Er-Jun,Hu, Zhi-Chao,Peng, Kang,Shi, Zhen,Wu, Yue-Xiao
, p. 5889 - 5894 (2021/11/27)
An efficient iodine-mediated construction of S?N bond was developed. Such a cross-dehydrogenative coupling of heterocyclic thiols with amines proceeded smoothly under metal-free and base-free conditions, and afforded a series of sulfenamides in good to excellent yields. The easily available substrates and convenient synthetic procedure illustrate potential synthetic value of this protocol for the preparation of sulfenamide related biologically or pharmaceutically active compounds.
The aqueous phase is generated in the catalytic molecular oxygen with S - N key of the sulfenamide compounds (by machine translation)
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Paragraph 0028, (2017/08/29)
The invention provides a water-phase catalytic molecular oxygen generation has S - N key of the sulfenamide compounds, in order to water-soluble transition metal phthalocyanine compound as a catalyst, in oxygen or in the air environment, the mercapto comp
Reusable cobalt-phthalocyanine in water: Efficient catalytic aerobic oxidative coupling of thiols to construct S-N/S-S bonds
Dou, Yingchao,Huang, Xin,Wang, Hao,Yang, Liting,Li, Heng,Yuan, Bingxin,Yang, Guanyu
supporting information, p. 2491 - 2495 (2017/07/17)
A new aerobic oxidative coupling of thiols in water to construct sulfenamides or disulfides was developed, utilizing cobalt(ii)phthalocyanine-tetra-sodium sulfonate as the catalyst and O2 as the oxidant. The mother liquor could be recycled up to 20 times with negligible loss of activity and only a minor decrease of product yield.
