29448-81-5 Usage
Uses
Used in Pharmaceutical Industry:
1H-Imidazo[4,5-b]pyridine-2-thiol is used as a building block for the synthesis of pharmaceuticals, due to its unique structure and potential for further chemical modifications. It contributes to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
1H-Imidazo[4,5-b]pyridine-2-thiol is used as a building block in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique structure allows for the creation of novel compounds with enhanced efficacy and selectivity in controlling pests and weeds.
Used in Dye and Pigment Industry:
1H-Imidazo[4,5-b]pyridine-2-thiol is used in the production of dyes and pigments, thanks to its ability to form colored compounds. It can be utilized in various applications, including textiles, plastics, and printing inks, to provide vibrant and stable colors.
Used in Antimicrobial Applications:
1H-Imidazo[4,5-b]pyridine-2-thiol exhibits antimicrobial properties, making it a potential candidate for the development of new antimicrobial agents. It can be used to combat bacterial and fungal infections, contributing to the discovery of novel treatments for various diseases.
Used in Antitumor Applications:
1H-Imidazo[4,5-b]pyridine-2-thiol has demonstrated antitumor activity, making it a promising compound for further research and development in cancer therapy. It can be used as a starting point for the synthesis of new anticancer drugs, potentially leading to more effective treatments for various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 29448-81-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,4,4 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 29448-81:
(7*2)+(6*9)+(5*4)+(4*4)+(3*8)+(2*8)+(1*1)=145
145 % 10 = 5
So 29448-81-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H5N3S/c10-6-8-4-2-1-3-7-5(4)9-6/h1-3H,(H2,7,8,9,10)
29448-81-5Relevant academic research and scientific papers
Lanthanide-catalyzed cyclocarbonylation and cyclothiocarbonylation: A facile synthesis of benzannulated 1,3-diheteroatom five- and six-membered heterocycles
Jing, Yufeng,Liu, Ruiting,Lin, Yanghui,Zhou, Xigeng
, p. 1117 - 1125 (2014/08/18)
La[N(SiMe3)2]3 proves to be an efficient catalyst system for the cyclocarbonylation of 1,2-disubstituted benzenes with isocyanates. In this approach, aryl/alkyl isocyanates react with o-phenylenediamine, o-aminophenol, o-aminothiophenol, catechols and anilines ortho-substituted by CH2NH2 and CONH2 to form, respectively, the corresponding benzimidazolones, benzoxazolones, benzothiazolones, benzodioxolones, 3,4-dihydroquinazolin-2(1H)-one, and quinazolinediones. These results represent the first example of lanthanide-catalyzed carbonylation. This methodology is also applicable for the preparation of various benzannulated 1,3-diheteroatom cyclic thioketones starting from aryl/alkyl isothiocyanates or CS2 in good to excellent yields. Based on the results of experiments performed using an o-aminobenzamido dianion lanthanide complex, a general mechanism, involving the tandem reaction of two lanthanide-ligand bonds with one heterocumulene molecule, is proposed as well.
A Facile Synthesis of 8-Arylamino- and 8-Hetarylaminopurines and their 1- and 3-Deaza Analogs
Garin, J.,Melendez, E.,Merchan, F. L.,Tejero, T.
, p. 867 - 870 (2007/10/02)
A general method for the synthesis of 8-arylamino- and 8-(2-benzothiazolylamino)-purines and their 1- and 3-deaza analogs is reported.The need for the presence of the desulfurizing agent in the preparation of the 8-arylamino derivatives is demonstrated an
