29450-07-5Relevant academic research and scientific papers
SYNTHESIS AND IONOPHORE PROPERTIES OF A SERIES OF NEW TETRAPYRAZOLIC MACROCYCLES
Tarrago, G.,Marzin, C.,Tep, A.,Zidane, I
, p. 91 - 100 (1988)
The synthesis of the several macrocycles containing two bipyrazolic subunits, with different cavity sizes and with donorgroup-bearing side arms attached, is reported.Their alkali cation binding ability has been studied from two aspects : extraction and transport through an artificial liquide membrane.Macrocycles described here show a high selectivity towars Li(1+) and Na(1+) cations; furthermore one of them is remarkably well adapted to extract selectively and to transport efficiently the lithium cation in competitive conditions.
SELECTIVE GLUCOCORTICOID RECEPTOR LIGANDS
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Page/Page column 34; 41; 42, (2015/06/03)
Described herein are certain steroid derivative compounds, for example of formula (I): wherein X1, X2, X3 L, and Ar are as defined herein, pharmaceutical compositions comprising such compounds, the use of such compounds and compositions to specifically target glucocorticoid action, and the use of such compounds and compositions in the treatment of acute and chronic inflammatory conditions, in particular rheumatoid arthritis, haematological and other malignancies, and for causing immunosuppression in the prevention or treatment of transplant rejection, as well as methods of preparing such compounds.
INDANE DERIVATES AS MUSCARINIC RECEPTOR AGONISTS
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Page 30, (2010/02/10)
The present invention relates to compounds of Formula I: I which are agonists of the M-1 muscarinic receptor.
Aminoalkyl-pyrazinones and -pyridones as thrombin inhibitors
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Page/Page column 22, (2010/02/11)
The invention relates to compounds of formula (I) wherein A, B, X, R1, R2, G, R3, D and E have the meaning as cited in the description and the claims. Said compounds are useful as coagulants. The invention also relates to the production and use thereof as medicament.
SUBSTITUTED 2H-[1,2,4]TRIAZOLO[4,3-A]PYRAZINES AS GSK-3 INHIBITORS
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Page/Page column 33, (2010/02/11)
The invention relates to compounds of formula (I) prodrugs thereof, and the pahrmaceutically acceptabel salts of the compounds and prodrugs, wherein Ra, Rb, R1 and R2 are as defined herein; pharmaceutical compositions thereof; and uses thereof.
MUSCARINIC AGONISTS
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Page 45-46, (2010/02/09)
The present invention relates to compounds of Formula (I): which are agonists of the M-1 muscarinic receptor.
Quinoline derivatives as antibacterials
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, (2008/06/13)
Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines
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Page/Page column 13, (2010/02/08)
The present invention provides compounds of formula (I) the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein Ra, Rb, R1, and R2 are as defined herein; pharmaceutical compositions thereof; and uses thereof.
Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents
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, (2008/06/13)
A series of alkyl ester and amide derivatives of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids, salts thereof and their preparation and use as antiulcer agents.
