294659-72-6Relevant articles and documents
Pyridoazepine derivative, pharmaceutical composition and applications thereof
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Paragraph 0125-0126; 0128, (2019/05/16)
The present invention discloses a pyridoazepine derivative, a pharmaceutical composition and applications thereof, wherein the pyridoazepine derivative (I), the isomer, the prodrug, the stable isotopederivative or the pharmaceutically acceptable salt thereof have the following structure. According to the present invention, the pyridoazepine derivative has good regulatory effects on TLR family andrelated signaling pathways, particularly on TLR8, can effectively treat, alleviate and/or prevent various diseases mediated by signaling pathways related to TLR family and TLR, and particularly can effectively treat, alleviate and/or prevent various TLR8 mediated diseases such as cancers, autoimmune diseases, infections, inflammations, transplant rejections, graft versus host diseases and the like. The formula (I) is defined in the specification.
IMIDAZO-, PYRAZOLOPYRAZINES AND IMIDAZOTRIAZINES AND THEIR USE
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Page/Page column 19, (2011/04/14)
The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological di
SUBSTITUTED PYRIDINES, AND USE THEREOF AS GSK3 INHIBITORS
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Page/Page column 11, (2011/08/08)
The invention relates to substituted pyridines and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of haematological disorders, preferably of leukopenia and neutropenia