294665-16-0Relevant academic research and scientific papers
Rhenium-catalyzed dehydrogenative olefination of C(sp3)-H bonds with hypervalent iodine(III) reagents
Gu, Haidong,Wang, Congyang
, p. 5880 - 5884 (2015)
A dehydrogenative olefination of C(sp3)-H bonds is disclosed here, by merging rhenium catalysis with an alanine-derived hypervalent iodine(iii) reagent. Thus, cyclic and acyclic ethers, toluene derivatives, cycloalkanes, and nitriles are all successfully alkenylated in a regio- and stereoselective manner.
Rate constants for 1,n-hydrogen transfer reactions in some amino acid derived radicals
Zeng, Le,Kaoudi, Talbi,Schiesser, Carl H.
, p. 7911 - 7914 (2007/10/03)
Absolute rate constants for 1,n-hydrogen atom transfers in some substituted amino acid derived radicals have been determined in benzene through the use of competitive kinetic experiments. Radicals derived from methyl N-(2-iodobenzoyl)-N-(tert-butyloxycarbonyl)glycinate, -alaninate, -leucinate, -tert-leucinate and -phenylglycinate undergo intramolecular 1,5-hydrogen atom transfer to afford the corresponding α-amino acid ester radicals with rate constants in the range: 1.0-4.3 × 107 s-1 at 80 °C. Where abstractable hydrogen atoms exist in the amino acid side-chain, 1,6- and 1,7-translocations are competitive processes.
Efficient Synthesis of Chiral Isoquinoline and Pyrido[1,2-b]-isoquinoline Derivatives via Intramolecular Heck Reactions
Sanchez-Sancho, Francisco,Mann, Enrique,Herradon, Bernardo
, p. 360 - 368 (2007/10/03)
The palladium(0)-catalyzed reaction of derivatives of γ-amino-α,β-unsaturated esters bearing an N-(2-iodobenzoyl) substituent results in an intramolecular Heck reaction, the outcome of which depends on the structure of the substrate as well as on the expe
Synthesis and reactions of amino acid-derived benziodazole oxides: New chiral oxidizing reagents
Zhdankin, Viktor V.,Smart, Jason T.,Zhao, Peng,Kiprof, Paul
, p. 5299 - 5302 (2007/10/03)
The novel benziodazole oxides (3) can be prepared by oxidation of the readily available 2-iodobenzamides (5 or 6) with potassium bromate. Benziodazole oxides can find practical application as selective oxidizing reagents analogous to the widely used Dess-
