294888-39-4

Upstream product

• 110317-48-1 methyl 2-amino-2-(1H-indol-3-yl)acetate 
• 501-53-1 benzyl chloroformate 
• 294888-41-8 (+/-)-N-benzyloxycarbonyl-3-indoleglycinate 
• 74-88-4 methyl iodide 
• 113975-75-0 methyl indol-3-ylglyoxylate oxime 
• 18372-22-0 2-(3-indolyl)oxoacetic acid methyl ester 
• 6747-15-5 α-amino-(+/)-3-indoleacetic acid 

Downstream Products

• 470670-88-3 (+/-)-methyl-N-benzyloxycarbonyl-1-tosyl-3-indoleglycinate 
• 294888-42-9 N-Cbz-indol-3-yl-N-methyl-O-methoxyglycinamide 
• 470670-73-6 2,5-dioxo-4-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-oxazolidine-3-carboxylic acid benzyl ester 
• 470670-87-2 (+/-)-N-benzyloxycarbonyl-1-tosyl-3-indoleglycine 

Relevant academic research and scientific papers

Development of a rapid, room-temperature dynamic kinetic resolution for efficient asymmetric synthesis of α-aryl amino acids

equation presented A rapid, highly efficient and general dynamic kinetic resolution (DKR) of racemic α-aryl UNCAs with the dual-function catalysis of modified cinchona alkaloid was accomplished at room temperature. This DKR led to the development of a highly enantioselective catalytic method for the practical synthesis of a wide range of α-aryl and α-heteroaryl amino acids in 89-92% ee and 86-95% yield from racemic UNCAs.

Syntheses of bis(3'-indolyl)-2(1H)-pyrazinones

The syntheses of 3,6-bis(3'-indolyl)-2(1H)-pyrazinone and 3,5- bis(3'indolyl)-2(1H)-pyrazinone were described. Syntheses of 3,6-bis(3'- indolyl)-2(1H)-pyrazinone proceeded through the condensation of N-Boc- indolylglycine with indol-3-yl-N-methyl-O-methox