29509-04-4

Usage

Uses

Used in Pharmaceutical Industry:
2,4,4-trimethyl-3-oxovaleronitrile is used as a precursor in the synthesis of various pharmaceuticals. Its role in the production of medicinal compounds is crucial due to its ability to be transformed into a wide range of active ingredients.
Used in Agrochemical Industry:
2,4,4-trimethyl-3-oxovaleronitrile is also utilized as a starting material in the synthesis of agrochemicals, contributing to the development of products that aid in crop protection and enhancement of agricultural yields.
Used in Organic Compounds Synthesis:
2,4,4-trimethyl-3-oxovaleronitrile is used as a building block in the production of various organic compounds, highlighting its versatility in chemical reactions and its importance in creating a diverse array of chemical products.
Used in Chemical Industry:
As a valuable intermediate, 2,4,4-trimethyl-3-oxovaleronitrile is employed in the manufacture of a variety of synthetic materials and products, underlining its significance in the broader chemical sector.
Safety Considerations:
It is important to handle 2,4,4-trimethyl-3-oxovaleronitrile with care and in accordance with proper safety protocols to ensure the safety of individuals and the environment.

InChI:InChI=1/C8H13NO/c1-6(5-9)7(10)8(2,3)4/h6H,1-4H3

Upstream product

• 598-98-1 Methyl pivalate 
• 107-12-0 propiononitrile 
• 59997-51-2 trimethylacetylacetonitrile 
• 151-50-8 potassium cyanide 
• 34916-32-0 1-Cyano-1-tert.-butyl-2-methyloxiran 

Downstream Products

• 159976-74-6 3-(1,1-dimethylethyl)-4-methyl-5-aminopyrazole 
• 120771-21-3 3-(tert-butyl)-4-methylisoxazol-5-amine 

Relevant academic research and scientific papers

Enantioselective dearomative [3+2] annulation of 5-amino-isoxazoles with quinone monoimines

The first enantioselective dearomative [3+2] annulation of 5-amino-isoxazoles with quinone monoimines was realized using a chiral phosphoric acid as catalyst. Various novel (bridged) isoxazoline fused dihydrobenzofurans bearing two continuous quaternary stereocenters were achieved in moderate to good yields (up to 94%) with moderate to good enantioselectivities (up to 98% ee). The absolute configurations of two products were assigned by X-ray crystal structural analyses and a plausible reaction mechanism was proposed. This journal is

Aryl Halides as Convenient Precursors of Electrogenerated Bases. Efficient Syntheses of β-Oxo Nitriles or Esters by Coupling Active-hydrogen Groups with Esters

In an undivided cell fitted with a sacrificial anode and a nickel cathode on which cadmium had been deposited, the electroreduction of aromatic halides affords a strong base which allows the effective synthesis of β-oxo nitriles or β-oxo esters from the coupling of active-hydrogen compounds with esters.

Process for the production of 3-oxonitriles

3-oxonitriles are produced by reaction of carboxylic acid esters with carboxylic acid nitriles in the presence of 70 to 80% suspension of sodium hydride in white oil. The oxonitrile are intermediate products for the production of 3-oxocarboxylic acid amides or esters and pesticides.