2952-05-8Relevant articles and documents
Thermal azide-Alkene cycloaddition reactions: straightforward multi-gram access to Δ2-1,2,3-Triazolines in deep eutectic solvents
Sebest, Filip,Casarrubios, Luis,Rzepa, Henry S.,White, Andrew J. P.,Díez-González, Silvia
supporting information, p. 4023 - 4035 (2018/09/11)
The multi-gram synthesis of a wide range of 1,2,3-Triazolines via azide-Alkene cycloaddition reactions in a Deep Eutectic Solvent (DES) is reported. The role of DES in this transformation as well as the origin of the full product distribution was studied with an experimental/computational-DFT approach.
A lithiomethyl trimethylammonium reagent as a methylene donor
Den Hartog, Tim,Sarria Toro, Juan M.,Couzijn, Erik P. A.,Chen, Peter
supporting information, p. 10604 - 10607 (2014/11/08)
Straightforward deprotonation of soluble tetramethylammonium salts with alkyllithium reagents gives lithiomethyl trimethylammonium reagents. Coordination of the Li cation is crucial to the stability of these 'N-C ylides'. These reagents were used to prepare epoxides, aziridines and allylic alcohols. This journal is the Partner Organisations 2014.
Novel aziridination of α-halo ketones: an efficient nucleophile-induced cyclization of phosphoramidates to functionalized aziridines
Yadav, Lal Dhar S.,Rai, Ankita,Rai, Vijai K.,Awasthi, Chhama
, p. 687 - 690 (2008/09/17)
A novel and efficient aziridination of α-halo ketones is reported. The reaction of α-halo ketones with diethyl N-arylphosphoramidates affords diethyl N-aryl-N-(2-oxoalkyl)phosphoramidates which undergo reductive (H--induced) cyclization with so