295321-74-3

Upstream product

• 4672-50-8 1,6-bis(p-toluenesulfonyloxy)hexane 
• 629-11-8 1,6-hexanediol 

Downstream Products

• 1002760-32-8 3-(2'-deoxy-β-D-ribofuranosyl)-6-(3-(6-fluorohexyloxy)phenyl)-2,3-dihydrofuro[2,3-d]pyrimidin-2(3H)-one 
• 1002760-31-7 3-(2'-deoxy-β-D-ribofuranosyl)-6-(4-(6-fluorohexyloxy)phenyl)-2,3-dihydrofuro[2,3-d]pyrimidin-2(3H)-one 

Relevant academic research and scientific papers

Deiodinative fluorination of alkyl iodide with p-iodotoluene difluoride

Oxidative fluorination of alkyl iodides with p-iodotoluene difluoride (4) was carried out. In the presence of Et3N-4HF, the fluorination reaction of prim-alkyl iodides selectively took place at the iodine position under mild conditions to give the corresponding alkyl fluorides in good yields.

Synthesis of [18F]-labeled (6-fluorohexyl)triphenylphosphonium cation as a potential agent for myocardial imaging using positron emission tomography

Lipophilic cations such as phosphonium salts penetrate the hydrophobic barriers of the plasma and mitochondrial membranes and accumulate in mitochondria in response to the negative inner-transmembrane potentials. Thus, as newly developed noninvasive imagi

A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression

We recently reported a new positron emission tomography (PET) reporter gene, namely, varicella-zoster virus thymidine kinase (VZV-tk) in combination, with carbon-11 or fluorine-18 labeled m-alkoxyphenyl bicyclic nucleoside analogues (BCNAs) as PET reporte

Electrochemical fluorodeiodination of alkyl iodides

Electrochemical oxidation of alkyl iodides using Et3N-nHF complexes as an electrolyte proceeds under mild conditions to give alkyl fluorides in good yields. The reaction is highly chemoselective and the functional groups in the substrate such as an ester, ketone, chloride, and tosylate could be tolerated under the reaction conditions.