29560-84-7

Usage

Uses

Used in Pharmaceutical Industry:
3-Chloroallyl alcohol is used as a key intermediate in the synthesis of Tafuramycin A, a potent anticancer and parasite attenuating agent. Its role in the production of this therapeutic compound highlights its importance in the development of treatments for cancer and parasitic infections.
Used in Chemical Synthesis:
3-Chloroallyl alcohol is utilized as a reagent in various chemical synthesis processes due to its reactive functional groups. Its ability to participate in a range of chemical reactions, such as substitution, addition, and elimination, makes it a versatile building block for creating a variety of compounds with different applications in the chemical and pharmaceutical industries.

InChI:InChI=1/C3H5ClO/c4-2-1-3-5/h1-2,5H,3H2/b2-1+

Upstream product

• 542-75-6 E/Z-1,3-Dichloropropene 
• 26438-85-7 3-chloro-2-fluoro-1-propanol 
• 64-17-5 ethanol 
• 563-57-5 3,3-dichloropropene 
• 10061-01-5 cis-1,3-Dichloropropene 
• 4643-05-4 (Z)-1-Chloro-1-propene-3-ol 

Downstream Products

• 64058-39-5 lactic acid-(3-chloro-allyl ester) 
• 91552-27-1 phenyl-carbamic acid-(3-chloro-allyl ester) 
• 6288-10-4 acrylic acid-(3-chloro-allyl ester) 
• 29516-63-0 2-((E)-3-Chloro-allyloxy)-1-methyl-3,5-dinitro-benzene 
• 107-19-7 propargyl alcohol 
• 627-30-5 1-chloro-3-hydroxypropane 
• 63270-87-1 N,N-di-n-propyl-3-aminopropenaldehyde 

Relevant academic research and scientific papers

Method and system for producing 1, 3-propylene glycol by multi-step method

The invention discloses a method and a system for producing 1, 3-propylene glycol by a multi-step method. The method comprises the following steps: carrying out dehydration reaction on 1, 3-dichloropropanol and a dehydration catalyst to prepare 1, 3-dichloropropene; carrying out a first hydrolysis reaction on a first mixed reaction system containing the 1, 3-dichloropropene, a first hydrolysis agent and a first solvent to prepare 3-chloro-2-propene-1-alcohol; carrying out hydrogenation reaction on the 3-chloro-2-propene-1-alcohol and a hydrogenation catalyst to prepare 3-chloropropanol; and carrying out a second hydrolysis reaction on a second mixed reaction system containing the 3-chloropropanol, a second hydrolysis agent and a second solvent to prepare the 1, 3-propylene glycol. According to the method, 1, 3-dichloropropanol is used as a raw material, the important chemical raw material 1, 3-propylene glycol is prepared through a dehydration, hydrolysis, hydrogenation and hydrolysisfour-step method, and the method has the advantages of mild reaction conditions, low cost, environmental protection, economy and the like.

Method for synthesizing propargyl alcohol

The invention discloses a method for synthesizing propargyl alcohol. The method includes hydrolyzing 1, 3-dichloropropene in saturated alkali metal carbonate solution to obtain 3-chloropropene alcohol; removing hydrogen chloride from the 3-chloropropene alcohol under the condition of the presence of a polar solvent dimethyl sulfoxide and hydroxide of alkali metal so as to obtain the propargyl alcohol. The method has the advantages that the 1, 3-dichloropropene is used as a raw material, the raw material can come from wide sources, is inexpensive and is easily available, the propargyl alcohol is easy to dehydrate, energy can be saved, and environments can be protected; the propargyl alcohol obtained by the aid of the method is high in yield and purity.

Novel photoreaction using diphenyl disulfide derivatives: Photoinduced oxidation of allyl alcohol

Allyl alcohols are oxidized to acrylaldehydes using diphenyl disulfide derivatives upon photoirradiation. The reaction occurs via α-hydrogen abstraction by a sulfanyl radical. Interestingly, the oxidation reaction occurs in moderate yield when a dendrimer disulfide is used as a mediator.