295793-38-3

Upstream product

• 295793-35-0 (6-methyl-1,3-benzodioxol-5-yl)-(4-nitrophenyl)-methanone 
• 452973-84-1 6-(4-nitro-benzoyl)-benzo[1,3]dioxole-5-carboxylic acid 
• 379733-75-2 7-methyl-5-(4-nitro-phenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isochromene 

Downstream Products

• 452974-03-7 (2-methyl-[1,3]dioxolan-2-ylmethyl)-[8-(4-nitro-phenyl)-[1,3]dioxolo[4,5-g]phthalazin-5-yl]-amine 
• 452973-96-5 3-butyl-5-(4-nitro-phenyl)-7,9-dioxa-1,2,3a,4-tetraaza-dicyclopenta[a,g]naphthalene 
• 452973-94-3 5-(4-nitro-phenyl)-3-trifluoromethyl-7,9-dioxa-1,2,3a,4-tetraaza-dicyclopenta[a,g]naphthalene 
• 452973-99-8 5-(4-nitro-phenyl)-3-pyridin-4-yl-7,9-dioxa-1,2,3a,4-tetraaza-dicyclopenta[a,g]naphthalene 
• 452973-98-7 3-cyclopropyl-5-(4-nitro-phenyl)-7,9-dioxa-1,2,3a,4-tetraaza-dicyclopenta[a,g]naphthalene 
• 452973-95-4 5-(4-nitro-phenyl)-3-propyl-7,9-dioxa-1,2,3a,4-tetraaza-dicyclopenta[a,g]naphthalene 
• 452974-10-6 3-ethoxy-5-(4-nitro-phenyl)-2,3-dihydro-7,9-dioxa-1,3a,4-triaza-dicyclopenta[a,g]naphthalene 
• 452974-02-6 (2,2-dimethoxy-ethyl)-[8-(4-nitro-phenyl)-[1,3]dioxolo[4,5-g]phthalazin-5-yl]-amine 

Relevant academic research and scientific papers

Triazolo- and imidazophthalazines, are they non-competitive AMPA antagonists?

Earlier structure-activity relationship studies within the 2,3-benzodiazepine family had revealed that the 3-acyl-4-methyl part of 2, an active non-competitive AMPA antagonist, can be substituted by condensed azole-rings at the same position preserving or

Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones

In this paper, we describe the synthesis of a series of novel substituted 4-aryl-6,7-methylenedioxyphthalazin-1(2H)-ones. The anticonvulsant activity of these compounds against audiogenic seizures was evaluated in DBA/2 mice after intraperitoneal (ip) inj