452974-06-0

Upstream product

• 452973-84-1 6-(4-nitro-benzoyl)-benzo[1,3]dioxole-5-carboxylic acid 
• 295793-38-3 8-(4-nitro-phenyl)-6H-[1,3]dioxolo[4,5-g]phthalazin-5-one 
• 379733-75-2 7-methyl-5-(4-nitro-phenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isochromene 
• 452973-87-4 5-chloro-8-(4-nitro-phenyl)-[1,3]dioxolo[4,5-g]phthalazine 
• 452974-02-6 (2,2-dimethoxy-ethyl)-[8-(4-nitro-phenyl)-[1,3]dioxolo[4,5-g]phthalazin-5-yl]-amine 

Relevant academic research and scientific papers

Triazolo- and imidazophthalazines, are they non-competitive AMPA antagonists?

Earlier structure-activity relationship studies within the 2,3-benzodiazepine family had revealed that the 3-acyl-4-methyl part of 2, an active non-competitive AMPA antagonist, can be substituted by condensed azole-rings at the same position preserving or