296244-55-8

Upstream product

• 13490-32-9 4-amino-N-hydroxy-furazan-3-carboxamidine 
• 147085-13-0 4-amino-N-hydroxy-1,2,5-oxadiazole-3-carboximidamidoyl chloride 

Downstream Products

• 1426930-78-0 3,4-bis[3-(p-methoxyphenyl)azofurazan-4-yl]furoxan 

Relevant academic research and scientific papers

Method for continuously preparing 3, 4-bis(4'-aminofurazan-3'-yl) furoxan by adopting micro-channel reactor

The invention discloses a method for continuously preparing 3, 4-bis(4'-aminofurazan-3'-yl) furoxan by adopting a micro-channel reactor The method comprises the following steps of (1) respectively pumping a 3-amino-4-amidoxime furazan solution and a sodium nitrite aqueous solution into a first micro-mixer in a micro-channel reactor device at the same time, mixing, and introducing into a first reaction module to carry out a first reaction, and (2) while the step (1) is carried out, respectively pumping the effluent of the first reaction module and a sodium carbonate solution into a second micro-mixer in the micro-channel reactor device at the same time, mixing, and introducing into the second reaction module to carry out a second reaction, thereby obtaining the effluent containing 3, 4-bis(4'-aminofurazan-3'-yl) furazan. The invention relates to an intermediate 3-amino-4-amidoxime furazan needing to be separated, and efficient and continuous preparation of 3, 4-bis(4'-aminofurazan-3'-yl) furoxan is realized through a one-pot two-step method.

Method for synthesizing 3, 4-bis(4'-aminofurazan-3'-yl) furoxan by one-step method

The invention belongs to the field of chemical synthesis, and particularly discloses a method for synthesizing 3, 4-bis(4'-aminofurazan-3'-yl) furoxan by a one-step method by using a micro-channel reactor. The method comprises the following steps of respectively pumping a 3, 4-bis(4'-aminofurazan-3'-yl) furoxan solution and a sodium nitrite aqueous solution into a micro-mixer of a micro-channel reactor at the same time, mixing, and introducing into the micro-reactor to react, thereby obtaining the reaction solution containing 3, 4-bis(4'-aminofurazan-3'-yl) furoxan. The reaction process provided by the invention realizes one-step direct synthesis from the raw material AAOF to the target product DATF, has the advantages of short reaction time, high raw material conversion rate, high targetproduct yield and the like, and has good industrial application prospects.

Synthesis and characterization of multicyclic oxadiazoles and 1-hydroxytetrazoles as energetic materials

[Figure not available: see fulltext.] Synthesis and characterization of several multicyclic oxadiazoles, 3,5-bis(4-nitrofurazan-3-yl)-1,2,4-oxadiazole, 3,3'-bis(4-nitrofurazan-3-yl)-5,5'-bi(1,2,4-oxadiazole), 3-(4-nitrofurazan-3-yl)-1,2,4-oxadiazol-5-amine, and salts of 1-hydroxytetrazoles, ammonium 5,5'-(1,2,4-oxadiazole-3,5-diyl)bis(1H-tetrazol-1-olate) and hydroxylammonium 5,5'-{[3,3'-bi(1,2,4-oxadiazole)]-5,5'-diyl}bis(1H-tetrazol-1-olate), as energetic materials are reported. Two of the compounds, 3,5-bis(4-nitrofurazan-3-yl)-1,2,4-oxadiazole and 3,3'-bis(4-nitrofurazan-3-yl)-5,5'-bi(1,2,4-oxadiazole), have attractive single crystal densities of 1.91 and 1.94 g·cm–3 (at 20°C), respectively. The design of these materials has been based on the idea that these multicyclic compounds with a 1,2,4-oxadiazole core will have good thermal stability and high density because of their 3,5-substitution pattern and the possibility of achieving a planar conformation. The various synthetic approaches and interesting chemistry observed during the construction of these new heterocycles has been described.

7,7 ’ -di (-furazan [3,4-b:3,4 ’ -d:3 ’ ’, 4 ’ ’ -f] azacycloheptene) compound

The invention discloses 7,7 '-di (-furazan [3,4-b:3,4' -d:3 ',4' -f]-azacycloheptene) compound, having a structural formula shown (I) . The invention is mainly used for mixing explosive.

Capture of 3-amino-4-oxycyanofurazan and characterization of isoxazole product

1,3-Dipolar cycloaddition reaction between nitrile oxide and alkyne was used to capture 3-amino-4-oxycyanofurazan (AOCF), which was considered as the key intermediate during the synthesis of 3,4-bis(4-aminofurazano-3-yl)furoxan (DATF) from 3-amino-4-chloroximinofurazan. The isolated isoxazoles from the reaction afforded evidences for the existence of AOCF. The structures of the isoxazoles were characterized by IR, 1H NMR, 13C NMR, MS, and elemental analysis. In addition, single crystal X-ray diffraction of one isoxazole was obtained.

3,6-Bis(4-nitro-1,2,5-oxadiazol-3-yl)-1,4,2,5-dioxadiazene (BNDD): A Powerful Sensitive Explosive

The explosive 3,6-bis(4-nitro-1,2,5-oxadiazol-3-yl)-1,4,2,5-dioxadiazene (BNDD) was synthesized by oxidation of the corresponding diamine using hydrogen peroxide in sulfuric acid with sodium tungstate. The product exhibited detonations during sensitivity testing at low insult; the material is shock and friction sensitive. The synthesis of BNDD should only be pursued by knowledgeable researchers exercising extreme caution.