296269-89-1

Upstream product

• 122-60-1 Phenyl glycidyl ether 
• 4769-73-7 (RS)-1-chloro-3-phenyloxy-2-propanol 
• 63715-95-7 1-O-acetyl-3-(phenoxy)propane-1,2-diol 
• 538-43-2 3-phenoxy-1,2-propanediol 
• 170375-42-5 (RS)-1-tert-butyldimethylsilyloxy-3-phenoxy-2-propanol 
• 237386-02-6 1-bromo-3-phenoxy-propan-2-one 
• 64-17-5 ethanol 
• 204584-17-8 1-acetoxy-3-phenoxy-acetone 

Downstream Products

• 538-43-2 (S)-3-phenoxy-1,2-propanediol 
• 82430-38-4 (S)-1-phenyl glycerol 

Relevant academic research and scientific papers

Oxidative cleavage of epoxides with ammonium molybdate-h2o2 system: An efficient route to α-hydroxy ketones

Epoxides are efficiently converted into α-hydroxy ketones by employing ammonium molybdate-H2O2 system. The α-hydroxy ketones are prepared without the formation of α-hydroxy aldehydes, via 1,2-diols as intermediates. The products are formed with excellent yields under very mild conditions.

A mild and efficient procedure for the oxidation of epoxides and aziridines using cerium(IV) ammonium nitrate and NBS

The CAN and NBS combination has been used for the first time for the synthesis of versatile α-hydroxy ketones and α-amino ketones from oxiranes/aziridines, respectively, in excellent yields. This method is a direct, one-pot, synthesis under mild conditions using acetonitrile-water (9:1) as solvent.

Microbial asymmetric reduction of α-hydroxyketones in the anti-Prelog selectivity

Yamadazyma farinosa IFO 10896 was found to reduce α-hydroxyketones bearing a phenyl ring to give optically active diols with anti-Prelog selectivity. The distance between the carbonyl group and the phenyl ring was shown to have an interesting effect on the reactivity and selectivity of the enzyme system.