2964-04-7

Basic information

• Product Name: d-N-Isopropylnorepinephrine
• Synonyms: (S)-(+)-Isoproterenol;(S)-Isoprenaline;(S)-Isoproterenol;1,2-Benzenediol, 4-[(1S)-1-hydroxy-2-[(1-methylethyl)amino]ethyl]- (9CI);1,2-Benzenediol, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, (S)-;d-Isoprenaline;d-Isoproterenol;d-N-Isopropylnorepinephrine
• CAS NO: 2964-04-7
• Molecular Formula: C₁₁H₁₇NO₃
• Molecular Weight: 211.26
• Mol File: 2964-04-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 417.5°Cat760mmHg
• Flash Point: 179.7°C
• Appearance: /
• Density: 1.199g/cm³
• CAS DataBase Reference: d-N-Isopropylnorepinephrine(CAS DataBase Reference)
• NIST Chemistry Reference: d-N-Isopropylnorepinephrine(2964-04-7)
• EPA Substance Registry System: d-N-Isopropylnorepinephrine(2964-04-7)

Safety Data

• Hazardous Substances Data: 2964-04-7(Hazardous Substances Data)

Upstream product

• 7683-59-2 isoproterenol 

Downstream Products

• 121-28-8 Isoproterenone 

Relevant articles and documents

In-situ and one-step preparation of protein film in capillary column for open tubular capillary electrochromatography enantioseparation

In this work, the phase-transitioned BSA (PTB) film using the mild and fast fabrication process adhered to the capillary inner wall uniformly, and the fabricated PTB film-coated capillary column was applied to realize open tubular capillary electrochromatography (OT-CEC) enantioseparation. The enantioseparation ability of PTB film-coated capillary was evaluated with eight pairs of chiral analytes including drugs and neurotransmitters, all achieving good resolution and symmetrical peak shape. For three consecutive runs, the relative standard deviations (RSD) of migration time for intra-day, inter-day, and column-to-column repeatability were in the range of 0.3%–3.5%, 0.2%–4.9% and 2.1%–7.7%, respectively. Moreover, the PTB film-coated capillary column ran continuously over 300 times with high separation efficiency. Therefore, the coating method based on BSA self-assembly supramolecular film can be extended to the preparation of other proteinaceous capillary columns.

Application of cyclam-capped β-cyclodextrin-bonded silica particles as a chiral stationary phase in capillary electrochromatography for enantiomeric separations

Two novel types of substituted cyclam-capped β-cyclodextrin (β-CD)-bonded silica particles have been prepared and used as chiral stationary phases in capillary electrochromatography (CEC). The two stationary phases have a chiral selector with three recognition sites: β-CD, cyclam, and the latter's sidearm. They exhibit excellent enantioselectivities in CEC for a wide range of compounds as a result of the cooperative functioning of the anchored β-CD and cyclam. After inclusion of the metal ion (Ni2+) from the running buffer into the substituted cyclams and their sidearm ligands, the bonded stationary phases become positively charged and can provide extra electrostatic interactions with ionizable solutes and enhance the dipolar interactions with some polar neutral solutes. This enhances the host-guest interaction with some solutes and improves chiral recognition and enantioselectivity. These new types of stationary phases exhibit great potential for fast chiral separations in CEC.