29640-38-8

Basic information

• Product Name: 5-phenoxymethyl-2-phenyl-N-isopropyloxazolidine
• CAS NO: 29640-38-8
• Molecular Weight: 297.397
• Mol File: 29640-38-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-phenoxymethyl-2-phenyl-N-isopropyloxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenoxymethyl-2-phenyl-N-isopropyloxazolidine(29640-38-8)
• EPA Substance Registry System: 5-phenoxymethyl-2-phenyl-N-isopropyloxazolidine(29640-38-8)

Safety Data

• Hazardous Substances Data: 29640-38-8(Hazardous Substances Data)

Upstream product

• 7695-63-8 (+/-)-1-isopropylamino-3-phenoxypropan-2-ol 
• 100-39-0 benzyl bromide 

Relevant articles and documents

Synthesis of potentially β-blocking practolol derivatives: (E + Z)-3- [4-(3-iodoprop-2-enyloxycarbonylamino)phenoxy]-1-(isopropylamino)propan-2-ol

The iodinatied carbamates 3 (E + Z), with potential β-blocking properties, were synthesized. The first route chosen, from 4-aminophenol and the chloroformate 7, had to be abandoned because of the formation of the oxazolidinone 10 during the epoxidation step. The aminoalcohol 17 prepared from the practolol 1 finally gave the target compounds by condensation with the iodoallylic chloroformates 8 (E + Z). The secondary Boc-protected amine function was regenerated without removing the carbamate function situated in the p-postion, by using mild reaction conditions (1 N HCl).