29644-84-6Relevant academic research and scientific papers
A new and efficient one-pot synthesis of 2-hydroxy-1,4-dihydrobenzoxazines via a three-component Petasis reaction
Chouguiat, Louisa,Boulcina, Raouf,Carboni, Bertrand,Demonceau, Albert,Debache, Abdelmadjid
supporting information, p. 5124 - 5128 (2014/12/10)
The secondary amines synthesized by the reaction between 2-aminophenols and aromatic aldehydes, via the reduction of the corresponding imines, were employed in the synthesis of new 2-hydroxy-2H-1,4-benzoxazine derivatives through a one-pot Petasis multico
Hypervalent iodine(III) mediated synthesis of 2-substituted benzoxazoles
Prakash, Om,Batra, Anita,Sharma, Vijay,Saini, Rajesh K.,Verma, Rajender S.
, p. 1031 - 1034 (2007/10/03)
2-Substituted benzoxazoles (6a-j, 7a-e, 7j-l) have been synthesized via the oxidative intramolecular cyclization of Schiff's bases (4a-j, 5a-e, 5j-l) using iodobenzene diacetate (IBD) as an oxidant in dry methanol. A one-pot procedure for the synthesis of 6a-j, 7a-e and 7j-l starting from o-aminophenol/p-chloro-o- aminophenol and aldehydes has also been developed.
Synthesis of 2-arylbenzoxazoles via DDQ promoted oxidative cyclization of phenolic Schiff bases - A solution-phase strategy for library synthesis
Chang, Junbiao,Zhao, Kang,Pan, Shifeng
, p. 951 - 954 (2007/10/03)
The Schiff base derived from the condensation of o-aminophenol with benzaldehydes was induced to undergo oxidative cyclization in the presence of DDQ. The resulting 2-arylbenzoxazoles were separated from the reduced DDQ by product by treatment of reaction mixture with a strongly basic ion-exchange resin. The applicability of this chemistry to spatially separate library synthesis is demonstrated by the preparation of a 352-member library.
