29644-84-6

Basic information

• Product Name: 4-chloro-2-{[(E)-(4-methoxyphenyl)methylidene]amino}phenol
• CAS NO: 29644-84-6
• Molecular Formula: C₁₄H₁₂ClNO₂
• Molecular Weight: 261.7036
• Mol File: 29644-84-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 451.9°C at 760 mmHg
• Flash Point: 227.1°C
• Density: 1.2g/cm³
• Vapor Pressure: 8.77E-09mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 4-chloro-2-{[(E)-(4-methoxyphenyl)methylidene]amino}phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2-{[(E)-(4-methoxyphenyl)methylidene]amino}phenol(29644-84-6)
• EPA Substance Registry System: 4-chloro-2-{[(E)-(4-methoxyphenyl)methylidene]amino}phenol(29644-84-6)

Safety Data

• Hazardous Substances Data: 29644-84-6(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 95-85-2 2-hydroxy-5-chloro-aniline 

Downstream Products

• 891-15-6 5-chloro-2-(4-methoxyphenyl)benzo[d]oxazole 

Relevant articles and documents

A new and efficient one-pot synthesis of 2-hydroxy-1,4-dihydrobenzoxazines via a three-component Petasis reaction

The secondary amines synthesized by the reaction between 2-aminophenols and aromatic aldehydes, via the reduction of the corresponding imines, were employed in the synthesis of new 2-hydroxy-2H-1,4-benzoxazine derivatives through a one-pot Petasis multico

Synthesis of 2-arylbenzoxazoles via DDQ promoted oxidative cyclization of phenolic Schiff bases - A solution-phase strategy for library synthesis

The Schiff base derived from the condensation of o-aminophenol with benzaldehydes was induced to undergo oxidative cyclization in the presence of DDQ. The resulting 2-arylbenzoxazoles were separated from the reduced DDQ by product by treatment of reaction mixture with a strongly basic ion-exchange resin. The applicability of this chemistry to spatially separate library synthesis is demonstrated by the preparation of a 352-member library.