29654-55-5

Usage

Uses

Used in Dendrimers and Polymer Synthesis:
3,5-Dihydroxybenzyl alcohol is used as a dendrimer building block for the creation of complex and highly branched structures with potential applications in various fields, such as drug delivery, nanotechnology, and materials science.
Used in the Synthesis of Dendritic Polyether Macromolecules:
3,5-Dihydroxybenzyl alcohol is used as a monomer for the synthesis of a series of monodisperse dendritic polyether macromolecules, which can be further functionalized and utilized in various applications.
Used in Dimethylsilyl Linked Dendrimers:
3,5-Dihydroxybenzyl alcohol may be employed in the synthesis of dimethylsilyl linked dihydroxybenzyl alcohol based dendrimers, which can exhibit unique properties and find use in specialized applications.
Used in Research and Characterization:
The aggregation behavior of 3,5-dihydroxybenzyl alcohol based dendritic polymers has been investigated using dynamic light scattering and transmission electron microscopy, contributing to the understanding of their properties and potential uses.
Used in the Preparation of Carboxylate-Terminated Dendrimers:
3,5-Dihydroxybenzyl alcohol building block has been described in the preparation of dendritic polyether macromolecules with carboxylate groups as chain-ends, which can be used in various applications, such as catalysis, sensing, and drug delivery.

InChI:InChI=1/C7H8O3/c8-4-5-1-6(9)3-7(10)2-5/h1-3,8-10H,4H2

Upstream product

• 35354-30-4 3,5-diacetoxy-benzyl alcohol 
• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 26153-38-8 3,5-dihydroxybenzaldehyde 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 856077-23-1 3,5-bis-methoxycarbonyloxy-benzaldehyde 

Downstream Products

• 150550-98-4 3,5-bis[4-(methoxycarbonyl)phenylmethyl]benzyl alcohol 
• 150551-00-1 3,5-bis(3,5-bis(4-methoxycarbonylphenyl)benzyloxy)benzyl alcohol 
• 146670-58-8 C₅₃H₄₀N₄O₇ 
• 134868-84-1 3,5-bis(p-bromophenylmethyloxy)benzyl alcohol 
• 146670-57-7 3,5-di(4-cyanobenzyloxy)benzyl alcohol 
• 33617-40-2 5-(bromomethyl)benzene-1,3-diol 
• 70150-59-3 1-Hydroxy-3-oxo-5-hydroxymethyl-cyclohexen 
• 70150-66-2 5-methyl-3-hydroxycyclohex-2-enone 
• 104311-39-9 5-(bromomethyl)-1,3-phenylene diacetate 
• 29680-76-0 3,5-diacetoxybenzyl-(triphenyl)phosphonium bromide 
• 181426-25-5 C₂₉H₂₈O₁₁ 
• 181425-95-6 C₃₃H₃₆O₁₁ 
• 181426-31-3 C₆₅H₆₀O₂₃ 
• 181426-03-9 C₇₃H₇₆O₂₃ 

Relevant academic research and scientific papers

Resorcinarenes as templates: A general strategy for the synthesis of large macrocycles

The concept that resorcinarenes can be used as templates for the synthesis of large macrocycles is introduced. By way of example, previously inaccessible, aromatic crown ethers compounds are synthesized. Copyright

Rapid Chemical Synthesis of Self-Assembling Semi-Synthetic Proteins

The design of well-defined monodispersed self-assembling semi-synthetic proteins is emerging as a promising research avenue. These proteins hold great potential to be used as scaffolds for various protein nanotechnology applications. Currently, there are very few chemical methods reported; however, they suffer from elaborate multistep organic synthesis. Herein, we report a new chemical methodology for the rapid synthesis of a diverse set of semi-synthetic protein families, which include protein amphiphiles, facially amphiphilic protein-dendron conjugates, and pH-sensitive protein-dendron conjugates. This chemical method holds great potential to access a wide variety of semi-synthetic proteins in a short time.

Synthesis of 3, 5 - dihydroxy benzaldehyde method (by machine translation)

The invention discloses a method for synthesizing 3, 5 - dihydroxy benzaldehyde of the method, the synthetic route is: first 3, 5 - dihydroxy benzoic acid sodium borohydride, dimethyl sulfate, boric acid under the action of the three methyl ester intermediate B obtained, then intermediate B in chromium trioxide and sulfuric acid to obtain compound under the action of the C, i.e. 3, 5 - dihydroxy benzaldehyde; reaction is: The invention of mild synthetic conditions, the reaction yield is high, and the process of the method is simple, the raw material is cheap, simple and convenient operation, is extremely suitable for industrial production, has a very wide range of industrial application and market value. (by machine translation)

GENERATION-DEPENDENT SUPRAMOLECULAR ASSEMBLIES OF PROTEIN-DENDRON CONJUGATES

The present invention discloses monodisperse protein-dendron conjugates that self-assemble to generation-dependent supramolecular protein assemblies of different size and surface charges. The invention further provides a process for synthesis of protein-dendron conjugates containing hydrophobic dendron of different generations.

Synthesis method of resveratrol

The invention provides a synthesis method of resveratrol.The method includes the steps of dissolving 3,5-dihydroxybenzoic acid in solvent, conducting reaction on sodium borohydride and Lewis acid to obtain 3,5-dihydroxy-benzyl alcohol, conducting reaction on 3,5-dihydroxy-benzyl alcohol and triphenylphosphine hydrobromic acid in certain solvent to obtain corresponding phosphonium, and making the obtained phosphonium react with p-hydroxy benzaldehyde under the effect of strong alkali to directly obtain the product resveratrol.The preparation method includes few steps, precious metal catalysts are prevented from being used in protection and deprotection processes of phenolic hydroxyl groups in the technology, cost is low, operation is easy, reaction conditions are easy to achieve, and industrial production is facilitated.

Preparation method of 3,5-dihydroxybenzyl alcohol

The invention relates to a preparation method of a medical and chemical intermediate 3,5-dihydroxybenzyl alcohol. The method comprises the following steps of: with commercially available 3,5-dihydroxy-benzoic acid as a raw material, preparing 3,5-diacetoxybenzoic acid through an acetylation reaction; reducing carboxyl into alcohol by a sodium borohydride/iodine borohydride system; and finally, performing acetyl de-protection using a weak base solution to obtain the target product 3,5-dihydroxybenzyl alcohol. The synthesis path has the characteristics of cheap and easily available reagent, mild reaction conditions, easiness in operation, easiness in product separation, relatively high yield and the like.

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.

A convenient method to reduce hydroxyl-substituted aromatic carboxylic acid with NaBH4/Me2SO4/B(OMe)3

The reduction of hydroxyl-substituted aromatic carboxylic acid with NaBH4/Me2SO4/B(OMe)3 is described. Borane is generated by the reaction of NaBH4 with Me2SO4 in THF, which is as efficient as the commercial one. B(OMe)3 has been successfully applied to increase the reactivity and selectivity of this reaction. The optimum ratio of borane/B(OMe)3/acid is studied, and a variety of hydroxyl-substituted aromatic acids are reduced in good yields.

Synthesis of dendrimers with terminal formyl groups

A method for preparation of dendrons and dendrimers with formyl groups at the terminal aromatic rings, ether bonds in the branching blocks, and ester bonds in the core of the macromolecules is proposed. A way for the selective synthesis of p-hydroxymethylbenzaldehyde is described.

Magnesium-tin(II) chloride dihydrate: A new system for chemoselective reduction of aldehydes into alcohols in the presence of ketones, ketalization of ketones and dehalogenation of benzyl halides

Magnesium-tin (II) chloride dihydrate in THF efficiently reduced aldehydes into their corresponding alcohols chemoselectively in the presence of ketones, formed ketals with ketones and glycol and dehalogenated benzyl halides.