296794-90-6

Basic information

• Product Name: 5-(methyloxy)-2-(2-{5-[4-(methyloxy)phenyl]-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)phenol
• Synonyms: 5-(methyloxy)-2-(2-{5-[4-(methyloxy)phenyl]-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)phenol
• CAS NO: 296794-90-6
• Molecular Formula: C26H23N3O3S
• Molecular Weight: 457.54412
• Mol File: 296794-90-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(methyloxy)-2-(2-{5-[4-(methyloxy)phenyl]-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(methyloxy)-2-(2-{5-[4-(methyloxy)phenyl]-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)phenol(296794-90-6)
• EPA Substance Registry System: 5-(methyloxy)-2-(2-{5-[4-(methyloxy)phenyl]-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl}-1,3-thiazol-4-yl)phenol(296794-90-6)

Safety Data

• Hazardous Substances Data: 296794-90-6(Hazardous Substances Data)

Upstream product

• 60965-23-3 1-(ω-chloroacetyl)-2-hydroxy-4-methoxybenzene 
• 153332-05-9 1-thiocarbamoyl-5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazole 

Relevant articles and documents

Synthesis of some thiazolyl-pyrazoline derivatives and preliminary investigation of their hypotensive activity

Some 1-(4-arylthiazol-2-yl)-3,5-diaryl-2-pyrazoline derivatives were synthesized by reacting 1-thiocarbamoyl-3,5-diaryl-2-pyrazoline derivatives with phenacetylbromide in ethanol. The structural elucidation of the compounds were performed by IR, 1H-NMR and Mass spectral data and elemental analyses. The hypotensive activities of 13 compounds were evaluated by using the tail-cuff method. All examined compounds showed appreciable hypotensive activities. Clonidine was used as reference substance in the pharmacological evaluation. (C) 2000 Editions scientifiques et medicales Elsevier SAS.