29740-54-3Relevant academic research and scientific papers
Regioselectivity in a highly efficient, microwave-assisted epoxide aminolysis
Desai, Hinal,D'Souza, Brendan R.,Foether, Devin,Johnson, Benjamin F.,Lindsay, Harriet A.
, p. 902 - 910 (2008/01/06)
We have developed a microwave-assisted aminolysis of epoxides as an efficient method for synthesizing a number of β-amino alcohols. In most cases, including in reactions of amines with a trisubstituted epoxide, only one equivalent of amine is required to
CARBON-CARBON BOND FORMATION UNDER MILD CONDITIONS VIA TANDEM CATIONIC AZA-COPE REARRANGEMENT-MANNICH REACTIONS. A CONVENIENT SYNTHESIS OF POLYSUBSTITUTED PYRROLIDINES.
Overman,Kakimoto,Okazaki,Meier G. Patrick
, p. 6622 - 6629 (2007/10/02)
The reaction of aldehydes (or ketones) with 2-alkoxy(or hydroxy)-3-alkenamines achieves a general and high-yielding synthesis of polysubstituted 3-acylpyrrolidines (eq 5-9). This tandem cationic aza-Cope rearrangement-Mannich cyclization reaction (eq 1) o
