2976-84-3

Basic information

• Product Name: 4-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORIDE
• Synonyms: 4-(Methylamino)cyclohexanone;4-(MethylaMino)cyclohexan-1-one;4-methylaminocyclohekxanone;4-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORIDE;4-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORID
• CAS NO: 2976-84-3
• Molecular Formula: C₇H₁₃NO
• Molecular Weight: 127.1842
• Mol File: 2976-84-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 209.184 °C at 760 mmHg
• Flash Point: 90.795 °C
• Appearance: /
• Density: 0.969 g/cm³
• Vapor Pressure: 0.206mmHg at 25°C
• Refractive Index: 1.463
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORIDE(2976-84-3)
• EPA Substance Registry System: 4-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORIDE(2976-84-3)

Safety Data

• Hazardous Substances Data: 2976-84-3(Hazardous Substances Data)

Usage

General Description

4-(Methylamino)cyclohexanone hydrochloride is a chemical compound that belongs to the class of ketones. It is a white to off-white crystalline powder that is used in the synthesis of pharmaceuticals and agrochemicals. 4-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORIDE is commonly employed as an intermediate in the production of various drugs, including muscle relaxants and antiepileptic medications. It is also used in the synthesis of aspartate receptor antagonists and in the research of the central nervous system. In addition, 4-(Methylamino)cyclohexanone hydrochloride is known for its potential as a non-opioid analgesic and has been the subject of research aimed at developing new pain management drugs with reduced side effects.

InChI:InChI=1/C7H13NO/c1-8-6-2-4-7(9)5-3-6/h6,8H,2-5H2,1H3

Upstream product

• 4746-97-8 cyclohexanedione monoethylene ketal 
• 593-51-1 methylamine hydrochloride 
• 22906-85-0 4-methylamino-phenol; hydrochloride 
• 22348-44-3 trans-4-Methylamino-cyclohexanol 
• 166398-41-0 4-(N-methyl)aminocyclohexane ethylene acetal 

Downstream Products

• 1297611-94-9 4-(1H-Indol-3-yl)-N-methylcyclohex-3-enamine 
• 1312333-18-8 C₂₆H₄₁N₃ 
• 400899-84-5 tert-butyl N-methyl-N-(4-oxocyclohexyl)carbamate 
• 1086380-08-6 tert-butyl N-(trans-4-hydroxy-4-methylcyclohexyl)-N-methylcarbamate 
• 1086380-05-3 tert-butyl N-(cis-4-hydroxy-4-methylcyclohexyl)-N-methylcarbamate 
• 1086378-49-5 N-(cis-4-hydroxy-4-methylcyclohexyl)-N-methyl-2,1,3-benzoxadiazole-5-carboxamide 
• 2976-82-1 4--2,2,6,6-tetra-<2-cyan-aethyl>-cyclohexanon 
• 2976-88-7 4-Methylamino-2,2,6,6-tetra-<2-cyan-aethyl>-cyclohexanon 
• 82323-66-8 (+/-)-N-benzoyl-4-methylaminocycloheptanone 
• 2976-83-2 4--cyclohexanon 

Relevant articles and documents

A palladium/norbornene cooperative catalysis to access N-containing bridged scaffolds

A palladium/norbornene cooperative catalysis promoted annulation involving an ortho-C-H amination and intramolecular Heck cascade between aryl iodides and functionalized amination reagents is reported, thereby providing a highly convergent access to the u

Biotin tethered homotryptamine derivatives: High affinity probes of the human serotonin transporter (hSERT)

Quantum dot conjugates of compounds capable of inhibiting the serotonin transporter (SERT) could form the basis of fluorescent probes for live cell imaging of membrane bound SERT. Additionally, quantum dot-SERT antagonist conjugates may be amenable to flu

Method for preparing aromatic secondary amino compound

Disclosed are (1) a method for preparing an aromatic secondary amino compound which comprises reacting an N-cyclohexylideneamino compound in the presence of a hydrogen moving catalyst and a hydrogen acceptor by the use of a sulfur-free polar solvent and/or a cocatalyst, and (2) a method for preparing an aromatic secondary amino compound which comprises reacting cyclohexanone or a nucleus-substituted cyclohexanone, an amine and a nitro compound corresponding to the amine in a sulfur-free polar solvent in the presence of a hydrogen moving catalyst, a cocatalyst being added or not added. In a further aspect, a method is provided for the preparation of aminodiphenylamine by reacting phenylenediamine and cyclohexanone in the presence of a hydrogen transfer catalyst in a sulfur-free polar solvent while using nitroaniline as a hydrogen acceptor.