297757-34-7Relevant academic research and scientific papers
Synthesis, resolution and structure of axially chiral atropisomeric N- arylimides
Shimizu, Ken D.,Freyer, Heather O.,Adams, Richard D.
, p. 5431 - 5434 (2000)
Reported is the synthesis and structures of a new series of axially chiral molecules based on restricted rotation. The ortho-substituted N- arylimides have enantiomeric atropisomers that are stable and separable at room temperature. The compounds are notable for their ease of synthesis as well as positioning of functionality (a carboxylic acid and an amine) in a highly asymmetric configuration. (C) 2000 Published by Elsevier Science Ltd.
Guest-accelerated molecular rotor
Dial, Brent E.,Rasberry, Roger D.,Bullock, Brooke N.,Smith, Mark D.,Pellechia, Perry J.,Profeta, Salvatore,Shimizu, Ken D.
supporting information; experimental part, p. 244 - 247 (2011/03/19)
A molecular rotor was designed in which the rate of rotation is accelerated by guest complexation. The binding of an acetate guest to the urea groups lowers the barrier of the adjacent Caryl-Nimide bond by 2 to 4 kcal/mol. This behav
