29805-13-8

Basic information

• Product Name: 1-(2,4-dichlorophenyl)prop-2-yn-1-ol
• Synonyms: 1-(2,4-dichlorophenyl)prop-2-yn-1-ol
• CAS NO: 29805-13-8
• Molecular Formula: C9H6Cl2O
• Molecular Weight: 0
• Mol File: 29805-13-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 282.8°Cat760mmHg
• Flash Point: 118.9°C
• Appearance: /
• Density: 1.389g/cm³
• Vapor Pressure: 0.00155mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 1-(2,4-dichlorophenyl)prop-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dichlorophenyl)prop-2-yn-1-ol(29805-13-8)
• EPA Substance Registry System: 1-(2,4-dichlorophenyl)prop-2-yn-1-ol(29805-13-8)

Safety Data

• Hazardous Substances Data: 29805-13-8(Hazardous Substances Data)

Usage

Description

1-(2,4-dichlorophenyl)prop-2-yn-1-ol, also known as propargyl 2,4-dichlorophenyl ether, is a chemical compound with the molecular formula C9H6Cl2O. It is a white to off-white solid with a molecular weight of 191.05 g/mol. 1-(2,4-dichlorophenyl)prop-2-yn-1-ol is commonly used in organic synthesis and pharmaceutical research as a reagent and intermediate. It has also been studied for its potential antibacterial and antifungal properties. Additionally, it is utilized in the production of various pharmaceuticals, agrochemicals, and other specialty chemicals due to its versatile reactivity and functional group compatibility. Furthermore, 1-(2,4-dichlorophenyl)prop-2-yn-1-ol has shown promise in the field of material science for its potential use in the development of new types of polymers and materials.

Uses

Used in Pharmaceutical Research:
1-(2,4-dichlorophenyl)prop-2-yn-1-ol is used as a reagent and intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapies.
Used in Agrochemical Production:
1-(2,4-dichlorophenyl)prop-2-yn-1-ol is used as a key intermediate in the production of agrochemicals, which are essential for the agricultural industry to protect crops and enhance yield.
Used in Specialty Chemicals:
1-(2,4-dichlorophenyl)prop-2-yn-1-ol is utilized in the creation of specialty chemicals, which have specific applications in various industries, such as coatings, adhesives, and sealants.
Used in Material Science:
In the field of material science, 1-(2,4-dichlorophenyl)prop-2-yn-1-ol is used for its potential in developing new types of polymers and materials, which could have a wide range of applications in different industries.
Used in Antibacterial and Antifungal Applications:
1-(2,4-dichlorophenyl)prop-2-yn-1-ol has been studied for its potential antibacterial and antifungal properties, making it a candidate for use in the development of new antimicrobial agents to combat resistant infections.

InChI:InChI=1/C9H6Cl2O/c1-2-9(12)7-4-3-6(10)5-8(7)11/h1,3-5,9,12H

Upstream product

• 108-05-4 vinyl acetate 
• 65032-27-1 ethynylmagnesium chloride 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 1187388-01-7 C₁₀H₆Cl₂O₃ 
• 4301-14-8 acetylenemagnesium bromide 

Downstream Products

• 1443225-51-1 (2,4-dichlorophenyl)(1-((pyridin-4-yl)methyl)-1H-1,2,3-triazol-4-yl)methanone 
• 1443225-50-0 (1-((5-chlorothiophen-2-yl)methyl)-1H-1,2,3-triazol-4-yl)(2,4-dichlorophenyl)methanone 
• 1443225-40-8 (1-benzyl-1H-1,2,3-triazol-4-yl)(2,4-dichlorophenyl)methanone 
• 1443225-53-3 ethyl 2-[4-(2,4-dichlorobenzoyl)-1H-1,2,3-triazol-1-yl]acetate 
• 1606139-41-6 C₁₈H₁₅Cl₂NO₃S 

Relevant articles and documents

ANTIVIRAL COMPOUNDS

The present invention relates to a compound of formula (I): to compositions comprising it and to their use in the prevention and/or treatment of viral infections, and in particular by a non-enveloped DNA virus and/or an enveloped RNA virus. The inventors found that the composed of formulae (I), (II) and (III), as defined herein, represent a novel class of antiviral agents with broad applicability against a wide spectrum of viruses.

NOVEL ANTIVIRAL COMPOUNDS

The present invention relates to a compound of formula (I): for use in the prevention and/or treatment of viral infections, and in particular by a non- enveloped DNA virus and/or an enveloped RNA virus. The present invention also relates to compounds of formula (II): and to compositions comprising it. The inventors found that imidazole derivatives of formula (I) and (II), as defined herein, represent a novel class of antiviral agents with broad applicability against a wide spectrum of viruses.

Silver(I)-catalyzed reaction between pyrazole and propargyl acetates: Stereoselective synthesis of the scorpionate ligands (E)-allyl-gem-dipyrazoles (ADPs)

The reaction between readily accessible pyrazole and propargyl acetates in the presence of Ag(I) catalyst yielded a new class of (E)-allyl-gem-dipyrazole scorpionate ligands: 1-aryl-2-N-pyrazolyl allyl acetates and 1,3-dipyrazolyl-3-arylpropene. The reaction showed broad substrate scope, and various functional and protecting groups were tolerated under the reaction conditions. The palladium(II) scorpionate complex could thus be easily prepared and successfully employed in Suzuki-Miyaura cross-couplings in water.