2981-00-2Relevant academic research and scientific papers
Metal-free photo-induced radical C-P and C-S bond formation for the synthesis of 2-phosphoryl benzothiazoles
Yang, Wenchao,Li, Bing,Zhang, Mingming,Wang, Shuang,Ji, Yigang,Dong, Sa,Feng, Jianguo,Yuan, Shuzhong
, p. 1313 - 1316 (2020)
We reveal here a visible-light promoted phosphorylation of 2-isocyanoaryl thioethers for the first time with concomitant C(sp3)-S bond cleavage and imidoyl C–S formation. Additionally, this method features the use of 3 mol% organic dye Rose Bengal as the photocatalyst without external transition-metal or peroxide oxidants, and provides a novel and environmentally friendly approach for the preparation of a variety of 2-phosphoryl benzothiazoles in moderate to good yields.
Cascade C(sp3)-S Bond Cleavage and Imidoyl C-S Formation: Radical Cyclization of 2-Isocyanoaryl Thioethers toward 2-Substituted Benzothiazoles
Yang, Wen-Chao,Wei, Kai,Sun, Xue,Zhu, Jie,Wu, Lei
, p. 3144 - 3147 (2018/05/28)
A cascade radical cyclization of 2-isocyanoaryl thioethers with H-phosphorus oxides, organoboronic acids, or alkyl radical precursors has been efficiently developed, providing a novel and highly efficient methodology to structurally diverse C2-substituted benzothiazole derivatives with broad functional group tolerance and good yields. This cascade radical process achieves the first cycloaddition of an imidoyl radical from isocyanide to sulfur atom, rending C(sp2)-S bond formation.
ortho-Lithiophenyl isocyanide: A versatile precursor for 3H-quinazolin-4-ones and 3H-quinazolin-4-thiones
Lygin, Alexander V.,De Meijere, Armin
supporting information; experimental part, p. 389 - 392 (2009/09/05)
(Chemical Equation Presented) ortho-Lithiophenyl isocyanide has been generated from ortho-bromophenyl isocyanide and successfully employed toward the synthesis of 2-substituted phenyl Isocyanides as well as 2,3-disubstituted 3H-quinazoline-4-ones and 3H-q
