29833-52-1Relevant academic research and scientific papers
KINETICS AND MECHANISM OF ACID HYDROLYSIS OF N-BENZOYL-L-LYSINES
Muzalewski, Feliks,Ciurak, Marek
, p. 931 - 940 (2007/10/02)
Minor differences in acid hydrolysis rates of α- and ε-amide bonds in corresponding N-benzoyl-L-lysines have been found.The reaction is accelerated in the presence of free carboxyl group in the lysine-derivative molecule.The acid dissociation constants KAH of N - and Nε-benzoyl-L-lysines have been determined.Also the substituent effect in benzoyl group on the reaction rate has been examined.A mechanism of the acid hydrolysis of acyl derivatives of lysine is proposed.
