29866-38-4

Upstream product

• 75-15-0 carbon disulfide 
• 140-29-4 phenylacetonitrile 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 75564-10-2 3-mercapto-4-phenyl-3-isothiazoline-5-thione 
• 31413-60-2 2-phenyl-3,3-dichloroacrylonitrile 

Downstream Products

• 128039-32-7 3-amino-5-methylthio-4-phenylpyrazole 
• 128118-86-5 Phenyl-thiazolidin-(2Z)-ylidene-acetonitrile 
• 128039-60-1 2,5-bis(methylthio)-11-methyl-3-phenyl-6,7-dihydro<1>benzothiepino<4,5-e>pyrazolo<1,5-a>pyrimidine 
• 128039-43-0 2,5-bis(methylthio)-3-phenyl-7,8-dihydro-6H-benzocyclohepta<2,1-e>pyrazolo<1,5-a>pyrimidine 
• 128039-40-7 2,5-bis(methylthio)-3-phenyl-7-(6-phenyl-1,3,5-hexatrienyl)pyrazolo<1,5-a>pyrimidine 
• 128039-39-4 2,5-bis(methylthio)-7-(4-methoxystyryl)-3-phenylpyrazolo<1,5-a>pyrimidine 
• 128039-38-3 2,5-bis(methylthio)-7-(4-methoxyphenyl)-3-phenylpyrazolo<1,5-a>pyrimidine 
• 128039-50-9 2,5-bis(methylthio)-3-phenyl-7-(4-phenyl-1,3-butadienyl)pyrazolo<1,5-a>pyrimidine 
• 128039-48-5 2,5-bis(methylthio)-3,7-diphenyl-6-methylpyrazolo<1,5-a>pyrimidine 
• 128083-30-7 7-(6-phenyl-n-hexyl)-3-phenylpyrazolo<1,5-a>pyrimidine 
• 128039-47-4 2,5-bis(methylthio)-6-n-butyl-7-methyl-3-phenylpyrazolo<1,5-a>pyrimidine 
• 128039-65-6 7-<2-(4-methoxyphenyl)ethyl>-3-phenylpyrazolo<1,5-a>pyrimidine 
• 128039-67-8 3-phenyl-7,8-dihydro-6H-benzocyclohepta<2,1-e>pyrazolo<1,5-a>pyrimidine 
• 128039-37-2 2,5-bis(methylthio)-7-methyl-3-phenylpyrazolo<1,5-a>pyrimidine 

Relevant academic research and scientific papers

A convenient one-pot synthesis of ketene dithioacetals

An easy synthesis of ketene dithioacetals 2 and 3 by the condensation of carbon disulfide and active methylene compounds 1 with subsequent alkylation in the presence of potassium fluoride is described.

Synthesis, Reactions, and Tautomerism of Ketene N,S-Acetals with Benzothiazoline Ring

Ketene dithioacetals 2 react with 2-aminothiophenol to afford the corresponding substituted 2(3H)-methylenebenzothiazoles 3.Some compounds 3 react with α,β-unsaturated esters to give 1H-pyridobenzothiazole derivatives 4 and 5 by an electrophilic addition and cyclocondensation sequence.

The Tautomerism between Ketene Aminals and Aminides

A tautomeric equilibrium between ketene aminals and amindines is disclosed as an electron-donating group is substituted at the para-position of the phenyl ring in 4.

Synthesis and X-Ray Structure Analysis of 2--imidazolidines, -hexahydropyrimidines, and -hexahydro-1H-1,3-diazepines

2--imidazolidines (7), -hexahydropyrimidines (8) and -hexahydro-1H-1,3-diazepines (9) were synthesized by the reaction of (dimethylthiomethylene)-phenylacetonitriles (6) with ethylenediamine, 1,3-diaminopropane and 1,4-diaminobutane,

1-Cyanoalkylidene-substituted 1,3-Dithietanones as Cyanothioketene Equivalents. Conversion into 1,3,5-Dithiazin-4-ones and 2-Azetidinethiones

Thiolation of 3,3-dichloroacrylonitriles 1 leads to dithiolates 3, which can be alkylated to give ketene dithioacetals 5 or acylated with phosgene to yield the title compounds 8. tert-Butyl(cyano)thioketene (9c) formed via cycloreversion of 8c was f

Studies on Heterocyclic Chemistry. Part 21. Reactions of 3-Mercapto- and 3-Acylthio-3-isothiazoline-5-thiones: Ring Transformations, a Base-induced Ring Cleavage, and Thiol-ester-Thioxo-ester Rearrangements

Acylation of 4-aryl-3-mercapto-3-isothiazoline-5-thiones (1) with acid chloride in pyridine or alternatively with acid anhydride leads exclusively to 3-acylthio-4-aryl-3-isothiazoline-5-thiones (2).Reactions of (1) with reactive acetylenes afford 2-aryl(