298689-33-5

Basic information

• Product Name: 2-amino-2-phenylbutyronitrile
• Synonyms: 2-amino-2-phenylbutyronitrile
• CAS NO: 298689-33-5
• Molecular Weight: 160.219
• Mol File: 298689-33-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-amino-2-phenylbutyronitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-2-phenylbutyronitrile(298689-33-5)
• EPA Substance Registry System: 2-amino-2-phenylbutyronitrile(298689-33-5)

Safety Data

• Hazardous Substances Data: 298689-33-5(Hazardous Substances Data)

Upstream product

• 71680-52-9 ammonium cyanide 
• 93-55-0 1-phenyl-propan-1-one 
• 151-50-8 potassium cyanide 
• 111035-95-1 2-hydroxy-2-ethyl-2-phenylacetonitrile 
• 143-33-9 sodium cyanide 
• 71-43-2 benzene 

Downstream Products

• 2216-93-5 5-ethyl-5-phenyl-imidazolidine-2,4-dione 
• 4896-15-5 2-acetylamino-2-phenyl-butyric acid 
• 5009-07-4 2-acetylamino-2-phenyl-butyronitrile 
• 5438-07-3 2-amino-2-phenylbutanoic acid 

Relevant articles and documents

Titanium-Catalyzed Cyano-Borrowing Reaction for the Direct Amination of Cyanohydrins with Ammonia

α-Aminonitrile was an important building block in natural products and key intermedia in organic chemistry. Herein, the direct amination of cyanohydrins with the partner of ammonia to synthesis N-unprotected α-aminonitriles is developed. The reaction proceeds via titanium-catalyzed cyano-borrowing reaction, which features high atom economy and simple operation. A broad range of ketone or aldehyde cyanohydrins was tolerated with ammonia, and the N-unprotected α-aminonitriles were synthesis with moderate to high yields under mild reaction conditions.

4-substituted quinoline derivatives

Disclosed are compounds of the Formula where R1, R2, R3, R4, X, Y1, and Y2are defined herein. These compounds bind with high affinity to NK-3 receptors and/or GABAAreceptors. Als