2987-42-0Relevant articles and documents
Copper-catalyzed ortho-halogenation of protected anilines
Urones, Beatriz,Martinez, Angel Manu,Rodriguez, Nuria,Arrayas, Ramon Gomez,Carretero, Juan C.
, p. 11044 - 11046 (2013)
A practical Cu-catalyzed direct ortho-halogenation of anilines under aerobic conditions has been developed. The reaction shows typically excellent mono-substitution selectivity, high ortho-regiocontrol and large functional group tolerance.