298700-57-9

Usage

Uses

Used in Pharmaceutical Industry:
(-)-EGCG-4'-O-ME is used as a therapeutic agent for its anti-inflammatory, antioxidant, and anti-cancer properties. It is being studied for its potential in treating various health conditions, including neurodegenerative diseases and metabolic disorders.
Used in Cosmetic Industry:
(-)-EGCG-4'-O-ME is used as an active ingredient in cosmetic products for its antioxidant and anti-inflammatory properties, which can help protect the skin from environmental stressors and promote a healthy complexion.
Used in Food and Beverage Industry:
(-)-EGCG-4'-O-ME can be used as a functional ingredient in food and beverage products to provide health benefits due to its antioxidant and anti-inflammatory properties. It may be incorporated into supplements, beverages, or food products to enhance their nutritional value and promote overall health.
Used in Research and Development:
(-)-EGCG-4'-O-ME is used as a subject of research in the development of new drugs and therapies. Its unique chemical properties and potential biological activities make it a promising candidate for further investigation into its therapeutic applications and mechanisms of action.

Upstream product

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Relevant academic research and scientific papers

Relationship between the biological activities of methylated derivatives of (-)-epigallocatechin-3-O-gallate (EGCG) and their cell surface binding activities

It was previously reported that (-)-epigallocatechin-3-O-gallate (EGCG) suppresses the expression of the high-affinity IgE receptor FcεRI in human basophilic cells and that this suppressive effect is associated with EGCG binding to the cell surface. This

Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol

An efficient and versatile synthetic method for labile polyphenols was established using 2-nitrobenzenesulfonate (Ns) as a protecting group for phenol. This methodology provides regio-and stereoselective access to a range of methylated catechins, such as methylated epigallocatechin gallates, that are not readily available from natural sources. In addition, biomimetic synthesis of theaflavins from catechins was accomplished using Ns protection to minimize undesired side reactions of electron-rich aromatic rings during oxidation, enabling construction of the complex benzotropolone core in a single-step oxidative coupling reaction. Availability of these compounds will aid detailed structure-biological activity relationship studies of catechins.

Solid-phase synthesis of a combinatorial methylated (±)- epigallocatechin gallate library and the growth-inhibitory effects of these compounds on melanoma B16 cells

We report on the solid-phase synthesis of a combinatorial methylated (±)-epigallocatechin gallate (EGCG) library and its biological evaluation. Epigallocatechin gallate (EGCG) and its methylated derivatives, which are members of the catechin family, exhib

Regioselective synthesis of methylated epigallocatechin gallate via nitrobenzenesulfonyl (Ns) protecting group

Regioselective synthesis of methylated epigallocatechin gallate from epigallocatechin was accomplished using a 2-nitrobenzenesulfonyl (Ns) group as a protecting group for phenols. This methodology provided several methylated catechins, which are naturally

Regiospecific and enantioselective synthesis of methylated metabolites of tea catechins

The regiospecific and enantioselective syntheses of various methylated regioisomers of epicatechin gallate (EGC) and epigallocatechin gallate (EGCG) have been achieved.