298708-79-9

Basic information

• Product Name: BAY41-4109 Racemic
• Synonyms: BAY41-4109 Racemic;Bay 41-4109 (racemate)
• CAS NO: 298708-79-9
• Molecular Formula: C₁₈H₁₃ClF₃N₃O₂
• Molecular Weight: 395.7629296
• EINECS: -0
• Product Categories: API
• Mol File: 298708-79-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• CAS DataBase Reference: BAY41-4109 Racemic(CAS DataBase Reference)
• NIST Chemistry Reference: BAY41-4109 Racemic(298708-79-9)
• EPA Substance Registry System: BAY41-4109 Racemic(298708-79-9)

Safety Data

• Hazardous Substances Data: 298708-79-9(Hazardous Substances Data)

Usage

Description

BAY41-4109 Racemic, also known as 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic Acid Methyl Ester, is an antiviral compound with potent activity against Hepatitis B Virus (HBV). It functions by inhibiting HBV replication through the destabilization of capsid assembly, making it a promising candidate for the treatment of HBV infections.

Uses

Used in Pharmaceutical Industry:
BAY41-4109 Racemic is used as an antiviral agent for the treatment of Hepatitis B Virus (HBV) infections. It targets the viral replication process by destabilizing the capsid assembly, which is crucial for the virus's ability to replicate and spread within the host.
Additionally, BAY41-4109 Racemic may be used as a research tool in the study of HBV replication mechanisms and the development of novel antiviral therapies. Its potent activity against HBV makes it a valuable compound for understanding the virus's life cycle and identifying potential therapeutic targets.

Upstream product

• 298709-29-2 3,5-difluoropyridine-2-carbonitrile 
• 298709-35-0 methyl 2-(2-chloro-4-fluorobenzylidene)-3-oxobutanoate 
• 298709-32-7 amino(3,5-difluoropyridin-2-yl)methaniminium chloride 

Downstream Products

• 360793-11-9 methyl (R)-6-bromomethyl-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridyl)-1,4-dihydropyrimidine-5-carboxylate 
• 1578153-29-3 (S)-4-[(R)-6-(2-chloro-4-fluoro-phenyl)-2-(3,5-difluoro-pyridin-2-yl)-5-methoxycarbonyl-3,6-dihydro-pyrimidin-4-ylmethyl]-morpholine-3-carboxylic acid 

Relevant articles and documents

HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

Medicaments against viral diseases

Novel dihydropyrimidines and combinations thereof with other antiviral agents, suitable for combating HBV infections.