2990-31-0

Usage

InChI:InChI=1/C9H10O3/c1-5-6(2)8(11)3-9(12)7(5)4-10/h3-4,11-12H,1-2H3

Upstream product

• 74-90-8 hydrogen cyanide 
• 527-55-9 4,5-dimethylresorcinol 
• 7647-01-0 hydrogenchloride 
• 60-29-7 diethyl ether 
• 519-42-6 5-methylorsellinic acid 

Downstream Products

• 5700-67-4 4,5,6-trimethyl-resorcinol 
• 34883-12-0 2-hydroxy-5,6-dimethyl-4-methoxybenzaldehyde 
• 34883-13-1 2,4-Dimethoxy-5,6-dimethylbenzaldehyd 
• 70979-84-9 2-Hydroxy-4-methoxy-5,6-dimethylbenzylalkohol 
• 934631-75-1 3-{3-[6-(tert-butyl-diphenyl-silanyloxymethyl)-4-methoxymethoxy-3,3-dimethyl-tetrahydro-pyran-2-yl]-1-methyl-2-triethylsilanyloxy-propyl}-6,8-bis-methoxymethoxy-5-methyl-isochroman-1-one 
• 934631-76-2 acetic acid 2-[2-acetoxy-3-(6,8-diacetoxy-5-methyl-1-oxo-isochroman-3-yl)-butyl]-6-(tert-butyl-diphenyl-silanyloxymethyl)-3,3-dimethyl-tetrahydro-pyran-4-yl ester 
• 934631-58-0 4,6-bis-methoxymethoxy-2,3-dimethyl-benzoic acid methyl ester 
• 647014-77-5 4-benzyloxy-6-hydroxy-2,3-dimethyl-benzaldehyde 

Relevant academic research and scientific papers

Aryl-aldehyde formation in fungal polyketides: Discovery and characterization of a distinct biosynthetic mechanism

Aryl-aldehydes are a common feature in fungal polyketides, which are considered to be exclusively generated by the R domain of nonreducing polyketide synthases (NR-PKSs). However, by cloning and heterologous expression of both cryptic NR-PKS and nonribosomal peptide synthase (NRPS)-like genes from Aspergillus terreus in Saccharomyces cerevisiae, we identified a distinct mechanism for aryl-aldehyde formation in which a NRPS-like protein activates and reduces an aryl-acid produced by the accompanying NR-PKS to an aryl-aldehyde. Bioinformatics study indicates that such a mechanism may be widely used throughout the fungi kingdom.

New heteroarotinoid compounds

Compounds of general formula (I): STR1 in which: R denotes a hydrogen atom, a halogen atom or a hydroxy, lower alkyl, lower alkyloxy, carboxyl, (lower alkyloxy)carbonyl, (lower arylalkyloxy)carbonyl, aminocarbonyl, (lower mono- or dialkyl)aminocarbonyl or (lower arylalkyl)aminocarbonyl group, an aminocarbonyl group N-substituted with a heterocyclic radical, or a thio, (lower alkyl)thio, sulfonyl or (lower alkyl)sulfonyl group, R1, R2, R3 and R4, which may be identical or different, denote a hydrogen atom, a halogen atom or a lower alkyl, lower alkenyl, lower alkyloxy or lower alkenyloxy group, optionally substituted with one or more halogen atoms, their isomers, enantiomers, diastereoisomers and also, when R denotes a carboxyl, their addition salts with a pharmaceutically acceptable base and, when R contains a basic group, their addition salts with a pharmaceutically acceptable acid.