299179-96-7

Upstream product

• 299179-95-6 C₂₅H₃₇BO₄Si 
• 299179-94-5 (2R,5S,6S,9R)-2-tert-Butyl-6-[(1E,5E,7E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-8-iodo-2,6-dimethyl-octa-1,5,7-trienyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-1,3-dioxa-spiro[4.5]dec-7-en-4-one 
• 496918-23-1 (2R,5S,6S,9R)-2-tert-Butyl-6-[(E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-5,6-dihydroxy-2-methyl-hex-1-enyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-1,3-dioxa-spiro[4.5]dec-7-en-4-one 
• 496918-01-5 (2E,6E)-(S)-7-[(2R,5S,6S,9R)-2-tert-Butyl-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-4-oxo-1,3-dioxa-spiro[4.5]dec-7-en-6-yl]-5-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-hepta-2,6-dienal 
• 496917-99-8 (E)-(S)-5-[(2R,5S,6S,9R)-2-tert-Butyl-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-4-oxo-1,3-dioxa-spiro[4.5]dec-7-en-6-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pent-4-enal 
• 214198-28-4 (2R,5S,6S,9R)-2-tert-Butyl-6-[(E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-hexa-1,5-dienyl]-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-1,3-dioxa-spiro[4.5]dec-7-en-4-one 
• 496917-94-3 (2R,2R',3S,4S,5R)-spiro-1-[(tert-butyldiphenylsilyloxy)methyl]-2-methyl-5-(3-hydroxy-2-methyl-1,5-hexadiene)cyclohex-1-yl-(4,5')-2'-tert-butyl-1',3'-dioxolan-4'-one 
• 496917-89-6 (2R,2R',4S,5R)-spiro-1-[(tert-butyldiphenylsilyloxy)methyl]-2-methyl-5-(2-methylpropen-1-ol)cyclohex-1-ene-(4,5')-2'-tert-butyl-1',3'-dioxolan-4'-one 
• 496917-91-0 (E)-3-[(2R,5S,6S,9R)-2-tert-Butyl-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-4-oxo-1,3-dioxa-spiro[4.5]dec-7-en-6-yl]-2-methyl-propenal 
• 496918-07-1 (2S,4S,5S)-5-(tert-butyldiphenylsilyloxy)-2,4-dimethyl-6-heptyn-1-ol 
• 146983-25-7 (E)-3-[(2R,5S,6S,9R)-2-tert-Butyl-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-4-oxo-1,3-dioxa-spiro[4.5]dec-7-en-6-yl]-2-methyl-acrylic acid ethyl ester 
• 147121-98-0 (2'S,4S,4'S,5'S)-3-<5'-<(tert-Butyldiphenylsilyl)oxy>-7'-dibromo-2',4'-dimethylhept-6'-enoyl>-4-isopropyl-1,3-oxazolidin-2-one 
• 147122-19-8 (2S,4S,5S)-5-<(tert-Butyldiphenylsilyl)oxy>-7-dibromo-2,4-dimethyl-6-heptenol 

Downstream Products

• 496917-82-9 C₇₇H₁₀₈O₈Si₃ 
• 496918-08-2 15-[2-tert-butyl-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-4-oxo-1,3-dioxa-spiro[4.5]dec-7-en-6-yl]-13-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxy)-2,4,10,14-tetramethyl-pentadeca-6,8,10,14-tetraenal 

Relevant academic research and scientific papers

Use of thallium(I) ethoxide in Suzuki cross coupling reactions

(equation presented) Thallium(I) ethoxide promotes Suzuki cross couplings for a range of vinyl-and arylboronic acids with vinyl and aryl halide partners in good to excellent yields. This reagent offers distinct advantages over thallium(I) hydroxide in terms of commercial availability, stability, and ease of use.

Studies on the synthesis of kijanolide: Synthesis of an advanced seco-acid intermediate

A synthesis of an advanced seco acid intermediate (7) in a projected total synthesis of kijanolide is described. Key steps in the synthesis of 7 include the highly diastereoselective allylation reaction of 15, the Suzuki cross coupling of dienyl iodide (11) and vinylboronic acid (12), and the IMDA reaction of 9. Elaboration of the spirotetronic acid unit of 7 was accomplished by a Dieckmann cyclization of the α-acetoxy ester intermediate derived from the IMDA cycloadduct (39).