299189-12-1Relevant academic research and scientific papers
DISULFIDE―CONFINED ARYLDIAZONIUM SALT COMPOUND AND METHOD FOR PREPARING THE SAME
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Paragraph 0075-0079, (2017/01/05)
The present invention relates to a disulfide-confined aryldiazonium(DSAD) salt compound, and to a producing method thereof and, more specifically, to a DSAD salt compound having a novel structure, and to a producing method which can efficiently synthesize the same. The DSAD salt compound enables the fixation of spatially-selective surface by simultaneously including a disulfide part activated by electrochemical oxidation and an aryldiazonium part which can be grafted on an electrode (ITO) or reduced graphene oxide (RGO), and can be helpfully used as a linker molecule for biomolecule fixation of an immunoassay and an immunological sensor platform.COPYRIGHT KIPO 2016
Lipoic acid derivatives, their preparation, and pharmaceutical compositions containing them
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, (2008/06/13)
The invention concerns novel lipoic acid derivatives, which have an inhibiting action with respect to NO-synthase enzymes producing nitrogen monoxide NO and/or are agents enabling the regeneration of antioxidants or entities trapping reactive oxygen speci
Novel lipoic acid analogues that inhibit nitric oxide synthase.
Harnett, Jeremiah J,Auguet, Michel,Viossat, Isabelle,Dolo, Christine,Bigg, Dennis,Chabrier, Pierre-E
, p. 1439 - 1442 (2007/10/03)
The synthesis and biological activity of novel lipoic acid analogues are reported. Lipoic acid and structural homologues coupled to arylthiophene amidine via carboxamide linkers are metabolic antioxidants capable of protecting neuronal cells against glutamate cytotoxicity, preventing loss of intracellular glutathione, and inhibit nitric oxide synthase.
