299209-93-1

Upstream product

• 79-20-9 acetic acid methyl ester 
• 299209-91-9 (R)-(+)-(3,4-dimethoxybenzylidene)-p-toluenesulfinamide 
• 299210-11-0 (R_S,S)-(-)-methyl-N-(p-toluenesulfinyl)-3-amino-3-(3,4-dimethoxyphenyl)propanoate 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 67-56-1 methanol 
• 10439-23-3 4-methylbenzenesulfinyl chloride 
• 247089-85-6 (R)-p-toluenesulfinamide 

Downstream Products

• 299210-01-8 (R_S,1S,3R)-(-)-1-N-(p-toluenesulfinyl)amino 1-(3,4-dimethoxyphenyl)-3-hydroxy-5-oxo-9-benzyloxynonane 
• 299210-03-0 (R_S,3R,5S)-(-)-methoxy-N-methyl-3-hydroxy-5-(3,4-dimethoxyphenyl)-5-N-(p-toluenesulfinyl)pentanamide 
• 299210-05-2 (2S,4S,6S)-(-)-2-(4-benzyloxy-butyl)-6-(3,4-dimethoxy-phenyl)-piperidin-4-ol 
• 299209-97-5 (4R,6S)-(-)-4-hydroxy-6-(3,4-dimethoxyphenyl)-piperidine-2-one 
• 263247-25-2 (2S,4S,6S)-(-)-2-(3,4-dimethoxyphenyl)-6-(4-hydroxybutyl)-piperidin-4-ol 
• 68681-73-2 (-)-(2S,4S,9aS)-2-hydroxy-4-(3,4-dimethoxyphenyl)-decahydroquinolizidine 
• 299209-95-3 (R_S,3R,5S)-(-)-methyl 3-hydroxy-5-N-(p-toluenesulfinyl)amino-5-(3,4-dimethoxyphenyl)pentanoate 

Relevant academic research and scientific papers

Asymmetric disulfonimide-catalyzed synthesis of δ-amino-β-ketoester derivatives by vinylogous Mukaiyama-Mannich reactions

An organocatalytic asymmetric synthesis of δ-amino-β-ketoester derivatives has been developed. A chiral disulfonimide (DSI) serves as a highly efficient precatalyst for a vinylogous Mukaiyama-Mannich reaction of readily available dioxinone-derived silylox

Alkaloid synthesis using chiral δ-amino β-ketoesters: A stereoselective synthesis of (-)-lasubine II

(equation presented) A highly stereoselective asymmetric synthesis of the quinolizidine alkaloid (-)-lasubine II from a δ-amino β-hydroxy ketone, a new polyfunctionalized chiral building block, is described.