2993-20-6

Basic information

• Product Name: 6-(trifluoromethyl)-5H-purin-2-amine
• Synonyms: 6-(trifluoromethyl)-5H-purin-2-amine
• CAS NO: 2993-20-6
• Molecular Formula: C₆H₄F₃N₅
• Molecular Weight: 203.12
• Mol File: 2993-20-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 227.8°C at 760 mmHg
• Flash Point: 91.6°C
• Appearance: /
• Density: 1.99g/cm³
• Vapor Pressure: 0.0758mmHg at 25°C
• Refractive Index: 1.699
• CAS DataBase Reference: 6-(trifluoromethyl)-5H-purin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(trifluoromethyl)-5H-purin-2-amine(2993-20-6)
• EPA Substance Registry System: 6-(trifluoromethyl)-5H-purin-2-amine(2993-20-6)

Safety Data

• Hazardous Substances Data: 2993-20-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H4F3N5/c7-6(8,9)3-2-4(12-1-11-2)14-5(10)13-3/h1-2H,(H2,10,11,12,14)

Upstream product

• 2927-10-8 6-trifluoromethyl-pyrimidine-2,4,5-triamine 
• 1869-10-9 5-nitro-6-trifluoromethyl-pyrimidine-2,4-diamine 
• 715-42-4 2,4-dichloro-5-nitro-6-trifluoromethyl-pyrimidine 
• 652-43-7 5-nitro-6-trifluoromethyl-1H-pyrimidine-2,4-dione 
• 792-18-7 5-phenylazo-6-trifluoromethyl-pyrimidine-2,4-diyldiamine 
• 222532-18-5 9-(Tetrahydropyran-2-yl)-2-<(tetrahydropyran-2-yl)amino>-6-(trifluoromethyl)purine 
• 19690-23-4 2-amino-6-iodopurine 
• 222532-13-0 6-Iodo-9-(tetrahydropyran-2-yl)-2-<(tetrahydropyran-2-yl)amino>purine 

Relevant articles and documents

Perfluoroalkylation of 6-iodopurines by trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(perfluoroalkyl)purine bases, nucleosides and acyclic nucleotide analogues

A Cul/KF mediated perfluoroalkylation reaction of various 9-substituted 6-iodopurines 1 with trimethyl(trifluoromethyl)silane or heptafluoropropyl(trimethyl)silane was used for the synthesis of the corresponding 6-(trifluoromethyl)-and 6-(heptafluoropropy