29938-64-5Relevant academic research and scientific papers
1-Alkylpyrazoles and 1-alkyl-5-chloropyrazoles from halovinyl ketones and 1,1-dialkylhydrazines
Bozhenkov,Savosik,Klyba,Zhanchipova,Mirskova,Levkovskaya
, p. 1194 - 1199 (2008)
Regioselective heterocyclization of alkyl 2-chloro-and 2,2-dichlorovinyl ketones with 1,1-dialkyl-hydrazines to 1,3-dialkyl-1H-pyrazoles and 1,3-dialkyl-5-chloro-1H-pyrazoles involves intermediate formation of the corresponding dialkylhydrazones. Fragment
New synthesis and properties of 3-alkyl-, 3-chloroalkyl-, 3-perfluoroalkyl-, and 3-aryl-1-methyl-(5-halo)pyrazoles from chloro(bromo) vinyl ketones and N,N-dimethylhydrazine
Levkovskaya,Bozhenkov,Larina,Mirskova
, p. 1501 - 1506 (2007/10/03)
A new regioselective heterocyclization was revealed in the reaction of 2-chloro- and 2,2-dichloro-(bromo)vinyl ketones with N,N-dimethylhydrazine to afford 3-substituted 1-methyl(5-halo)pyrazoles. The reaction is accompanied by elimination of methyl halide and formation of up to 90% of N,N,N-trimethylhydrazinium halide as the second product.
