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(S)-(+)-2-methoxy-2-(2-naphthyl)propionic acid, commonly known as Naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) characterized by its potent analgesic, antipyretic, and anti-inflammatory properties. It is a chiral molecule with the S-configuration and exhibits its pharmacological effects through the inhibition of cyclooxygenase enzymes, thereby reducing the synthesis of prostaglandins involved in pain and inflammation.

299397-14-1

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299397-14-1 Usage

Uses

Used in Pharmaceutical Industry:
Naproxen is used as an analgesic for the relief of mild to moderate pain, as an antipyretic to reduce fever, and as an anti-inflammatory agent to alleviate inflammation and swelling. Its application is particularly beneficial for conditions such as arthritis, menstrual cramps, and general aches and pains.
Used in Pain Management:
Naproxen serves as a pain management medication, helping to alleviate acute and chronic pain by inhibiting the production of prostaglandins, which are chemicals that contribute to the sensation of pain and inflammation in the body.
Used in Inflammation Treatment:
As an anti-inflammatory agent, Naproxen is utilized in the treatment of various inflammatory conditions, including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, by reducing the inflammation and associated discomfort.
Used in Over-the-counter Medications:
Naproxen is also found in over-the-counter (OTC) medications, making it accessible for individuals seeking relief from pain, fever, and inflammation without a prescription.
It is crucial to follow the recommended dosage and consult with a healthcare professional before using Naproxen, as it may have potential side effects and interact with other medications.

Check Digit Verification of cas no

The CAS Registry Mumber 299397-14-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,9,9,3,9 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 299397-14:
(8*2)+(7*9)+(6*9)+(5*3)+(4*9)+(3*7)+(2*1)+(1*4)=211
211 % 10 = 1
So 299397-14-1 is a valid CAS Registry Number.

299397-14-1Relevant academic research and scientific papers

Absolute configuration of 2-methoxy-2-(2-naphthyl)propionic acid as determined by the 1H NMR anisotropy method

Ichikawa, Akio,Hiradate, Syuntaro,Sugio, Akinori,Kuwahara, Shunsuke,Watanabe, Masataka,Harada, Nobuyuki

, p. 2669 - 2675 (2000)

2-Methoxy-2-(2-naphthyl)propionic acid 1 and 2-hydroxy-2-(2-naphthyl)propionic acid 2 were prepared by the Grignard reaction of 2-naphthylmagnesium bromide with (1R,2S,5R)-(-)-menthyl pyruvate. The absolute configurations of (+)-1 and (+)-2 were determined to be S by the 1H NMR anisotropy method. Copyright (C) 2000 Elsevier Science Ltd.

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