299430-04-9

Upstream product

• 116511-95-6 (benzenesulfonyl)methyllithium 
• 127516-28-3 (2R)-1-iodo-2-methyl-3-(tetrahydropyranyloxy)-propane 
• 3112-85-4 methylphenylsulfonate 
• 88557-53-3 (R)-2-Methyl-3-(tetrahydro-pyran-2-yloxy)-propionic acid methyl ester 
• 110-87-2 3,4-dihydro-2H-pyran 
• 88557-54-4 (2R)-2-methyl-3-(tetrahydro-2H-pyran-2-yloxy)propyl 4-methylbenzenesulfonate 
• 88588-59-4 (2S)-2-methyl-3-(tetrahydropyran-2-yloxy)propan-1-ol 

Downstream Products

• 299926-64-0 (2R,6R)-2,6-dimethyl-7-tetrahydropyranyloxyheptyl p-toleuenesulfonate 
• 299430-19-6 (2S,6R)-2,6-dimethyltetradecyl tosylate 
• 299430-10-7 (2S,6R)-2,6-dimethyl-14-pentadecenyl tosylate 
• 127750-73-6 (9E,13E)-(2R,4S,8S)-6-Benzenesulfonyl-17-(tert-butyl-dimethyl-silanyloxy)-4,8,10,14-tetramethyl-2-(2-methyl-[1,3]dioxolan-2-yl)-octadeca-9,13-dien-5-one 
• 121587-31-3 (4E,8E)-(S)-12-Benzenesulfonyl-4,8,10-trimethyl-dodeca-4,8-dienoic acid methyl ester 
• 121587-32-4 ((4E,8E)-(S)-12-Benzenesulfonyl-1,4,8,10-tetramethyl-dodeca-4,8-dienyloxy)-tert-butyl-dimethyl-silane 
• 127779-23-1 (5E,9E)-(S)-13-Benzenesulfonyl-5,9,11-trimethyl-trideca-5,9-dien-2-ol 
• 121587-30-2 (E)-(S)-8-Benzenesulfonyl-4,6-dimethyl-oct-4-enoic acid methyl ester 
• 127750-72-5 (E)-(S)-10-Benzenesulfonyl-2,6,8-trimethyl-deca-1,6-dien-3-ol 
• 127750-71-4 (S)-6-Benzenesulfonyl-2,4-dimethyl-hex-1-en-3-ol 
• 308357-64-4 (2S)-2-methyl-4-(phenylsulfonyl)butanal 
• 299430-05-0 (2S,4RS,6S)-1-tert-butyldimethylsilyloxy-2,6-dimethyl-4-phenylsulfonyl-7-tetrahydropyranyloxyheptane 
• 121587-29-9 (3S)-3-methyl-1-phenylsulfonylbutan-4-ol 

Relevant academic research and scientific papers

Pheromone synthesis, CCIS synthesis of the enantiomers of anti-2,6-dimethylheptane-1,7-diol monotetrahydropyranyl ether and their conversion into the enantiomers of the sex pheromone components of the apple leafminer, Lyonetia prunifoliella

Both (2R,6R)- and (2S,6S)-isomers of 2,6-dimethylheptane-1,7-diol monotetrahydropyranyl ether (4) were synthesized, and converted into the enantiomers of anti-10,14-dimethyl-1-octadecene (1), anti-5,9-dimethyloctadecane (2) and anti-5,9-dimethylheptadecane (3), the sex pheromone components of the apple leafminer (Lyonetia prunifoliella).

TOTAL SYNTHESIS OF A PUTATIVE TRIENE INTERMEDIATE IN MONENSIN BIOSYNTHESIS, ACTIVATED AS A CAPRYLCYSTEAMINE THIOL ESTER.

The total synthesis is reported, from a pool of optically pure starting materials, of a tritium labelled form of a putative intermediate in monensin biosynthesis, in which the terminal carboxyl group is activated as a caprylcysteamine thiol ester.