299435-95-3

Basic information

• Product Name: 2-fluorobenzaldehyde diethylacetal
• Synonyms: 2-fluorobenzaldehyde diethylacetal
• CAS NO: 299435-95-3
• Molecular Weight: 198.237
• Mol File: 299435-95-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-fluorobenzaldehyde diethylacetal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluorobenzaldehyde diethylacetal(299435-95-3)
• EPA Substance Registry System: 2-fluorobenzaldehyde diethylacetal(299435-95-3)

Safety Data

• Hazardous Substances Data: 299435-95-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 446-52-6 2-Fluorobenzaldehyde 

Relevant articles and documents

Development of a novel Br?nsted acid UiO-66 metal-organic framework catalyst by postsynthetic modification and its application in catalysis

A novel Br?nsted acid derived metal-organic framework (MOF) has been developed to serve as an efficient heterogeneous catalyst for the acetalization and Morita-Baylis-Hillman reaction. Aromatic sulfonic acid groups were successfully incorporated to the framework of UiO-66 by post-synthetic modifications using commercially available anhydridic reagents. The UiO-66-RArSO3H Br?nsted acid catalyst was fully characterized using SEM, PXRD, FTIR, TGA and N2 adsorption/desorption isotherms. Furthermore, efficient acetalization and Morita-Baylis-Hillman reactions were evaluated to demonstrate the high catalytic performance of the UiO-66-RArSO3H catalyst. The UiO-66-RArSO3H catalyst is compatible with a variety of substituted substrates and can be recycled five times without a compromise in the yield or selectivity.

Preparation of ascorbic acid intermediates

A synthetic route to ascorbic acid is provided in which a 3,5:4,6-protected derivative of gulonic acid is prepared from gulono-1,4-lactone. Oxidation of the derivative and hydrolysis of the resulting product affords 2-ketogulonic acid or ester thereof which can be readily converted to ascorbic acid by known methods.