299954-05-5

Basic information

• Product Name: 2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4 H-CYCLOPENTA[ B ]THIOPHENE-3-CARBOXYLIC ACID AMIDE
• Synonyms: TIMTEC-BB SBB009256;2-[(2-CHLOROACETYL)AMINO]-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXAMIDE;2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4 H-CYCLOPENTA[ B ]THIOPHENE-3-CARBOXYLIC ACID AMIDE;4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXAMIDE, 2-[(2-CHLOROACETYL)AMINO]-5,6-DIHYDRO-;AKOS B006561;ASINEX-REAG BAS 05125055;ART-CHEM-BB B006561
• CAS NO: 299954-05-5
• Molecular Formula: C₁₀H₁₁ClN₂O₂S
• Molecular Weight: 258.72
• Mol File: 299954-05-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4 H-CYCLOPENTA[ B ]THIOPHENE-3-CARBOXYLIC ACID AMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4 H-CYCLOPENTA[ B ]THIOPHENE-3-CARBOXYLIC ACID AMIDE(299954-05-5)
• EPA Substance Registry System: 2-(2-CHLORO-ACETYLAMINO)-5,6-DIHYDRO-4 H-CYCLOPENTA[ B ]THIOPHENE-3-CARBOXYLIC ACID AMIDE(299954-05-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 299954-05-5(Hazardous Substances Data)

Usage

Chemical class

Amide derivative of a cyclopenta[b]thiophene carboxylic acid

Structural feature

Contains a chloro-acetylamine group

Potential pharmaceutical applications

Antimicrobial or antifungal properties

Possible uses

Antibiotic or antifungal agent

Treatment target

Various infections

Current status

Requires further research and development to understand and utilize its potential pharmaceutical properties

Upstream product

• 77651-38-8 2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 1158839-03-2 2-(2-(3-cyclohexyl-3,4-dihydro-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 1158839-05-4 2-(2-(3-(3-fluorophenyl)-3,4-dihydro-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 1158839-09-8 2-(2-(3-(4-chlorophenyl)-3,4-dihydro-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 1158839-11-2 2-(2-(3-benzyl-3,4-dihydro-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 1158839-15-6 2-(2-(3-allyl-3,4-dihydro-4-oxo-5-(3-nitrophenyl)thieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 1158839-14-5 2-(2-(3-allyl-3,4-dihydro-4-oxo-5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 1158839-07-6 2-(2-(3-(4-nitrophenyl)-3,4-dihydro-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 315707-84-7 2-(2-(3-allyl-3,4-dihydro-4-oxo-5-phenylthieno[2,3-d]pyrimidin-2-ylthio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 
• 315676-59-6 2-(2-(3-allyl-3,4,5,6,7,8-hexahydro-4-oxo-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylthio)acetamido)5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide 

Relevant articles and documents

2-(3,4-dihydro-4-oxothieno[2,3-d]pyrimidin-2-ylthio) acetamides as a new class of falcipain-2 inhibitors. 3. design, synthesis and biological evaluation

The cysteine protease falcipain-2 (FP-2) of Plasmodium falciparum is a principal cysteine protease and an essential hemoglobinase of erythrocytic P. falciparum trophozoites, making it become an attractive target enzyme for developing anti-malarial drugs.