300-42-5 Usage
Uses
A CNS stimulant. Anorexic. In attention deficit disorder with hyperactivity.
Controlled substance (stimulant).
General Description
Odorless white crystals or fluffy crystalline powder. Bitter taste. pH (aqueous solutions) about 6.
Air & Water Reactions
Water soluble.
Reactivity Profile
An acidic salt of the amine, therefore behaves as a weak acid.
Fire Hazard
Flash point data for N,alpha-dimethylphenethylamine hydrochloride are not available; however, N,alpha-dimethylphenethylamine hydrochloride is probably combustible.
Safety Profile
Poison by ingestion,
intravenous, intraperitoneal, subcutaneous,
and intramuscular routes. Human systemic effects by ingestion: altered sleep patterns,
anorexia, and change in heart rate.
Experimental reproductive effects. An eye
irritant, A powerful central nervous system
stimulant. When heated to decomposition it
emits very toxic fumes of NOx and HCl. See
also BENZEDRINE.
Check Digit Verification of cas no
The CAS Registry Mumber 300-42-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,0 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 300-42:
(5*3)+(4*0)+(3*0)+(2*4)+(1*2)=25
25 % 10 = 5
So 300-42-5 is a valid CAS Registry Number.
300-42-5Relevant articles and documents
Significant determinants of isotope composition during HI/Pred synthesis of methamphetamine
David, Gabrielle E.,Hibbert, D. Brynn,Frew, Russell D.,Hayman, Alan R.
, p. 22 - 29 (2010)
Methamphetamine HCl was synthesized using three variations of the hydriodic acid/red phosphorus (HI/Pred) synthetic route. A Plackett-Burman experimental design was used to determine how reaction parameters affected the isotopic composition of the product. Isotope ratio mass spectrometry results showed only the source of precursor 13C was significant in determining product δ13C; the manufacturer, reaction temperature, time, scale, and source of HI were not significant. The precursor was also the main determinant of product δ2H, with smaller contributions from the HI source for one method. From precursor to product, large δ2H depletion occurred for most samples. Deuterium nuclear magnetic resonance spectroscopy (2H NMR) was used to investigate the specific site of this. Significant fraction of deuterium was observed only at the benzylic position, the site of hydrogen addition during synthesis. Methamphetamine synthesized from ephedrine was shown to be depleted in this position.