3001-06-7

Upstream product

• 104-03-0 4-nitrobenzeneacetic acid 
• 3011-34-5 4-hydroxy-3-nitrobenzaldehyde 
• 100-13-0 4-nitrostyrene 
• 51288-37-0 N-(4-hydroxy-3-nitrophenyl)acetamide 
• 555-16-8 4-nitrobenzaldehdye 
• 1252036-52-4 4-hydroxy-3-nitrobenzenediazonium tetrafluoroborate 

Relevant academic research and scientific papers

Scope and limitations of the Heck-Matsuda-coupling of phenol diazonium salts and styrenes: A protecting-group economic synthesis of phenolic stilbenes

4-Phenol diazonium salts undergo Pd-catalyzed Heck reactions with various styrenes to 4′-hydroxy stilbenes. In almost all cases higher yields and fewer side products were observed, compared to the analogous 4-methoxy benzene diazonium salts. In contrast, the reaction fails completely with 2- and 3-phenol diazonium salts. For these substitution patterns the methoxy-substituted derivatives are superior. The Royal Society of Chemistry 2013.

A deacetylation-diazotation-coupling sequence: Palladium-catalyzed C-C bond formation with acetanilides as formal leaving groups

Acetanilides can be deacetylated and diazotized in situ, and subsequently used in Pd-catalyzed coupling reactions without isolation of the diazonium intermediate. Heck reactions, Suzuki crosscoupling reactions, and a Pd-catalyzed [2+2+1] cycloaddition hav