30011-66-6

Basic information

• Product Name: Benzene, 1-(3-buten-1-ynyl)-4-methyl-
• CAS NO: 30011-66-6
• Molecular Formula: C11H10
• Molecular Weight: 142.2
• Mol File: 30011-66-6.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(3-buten-1-ynyl)-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(3-buten-1-ynyl)-4-methyl-(30011-66-6)
• EPA Substance Registry System: Benzene, 1-(3-buten-1-ynyl)-4-methyl-(30011-66-6)

Safety Data

• Hazardous Substances Data: 30011-66-6(Hazardous Substances Data)

Upstream product

• 87639-42-7 4-p-tolylbut-3-yn-1-yl tosylate 
• 104-87-0 4-methyl-benzaldehyde 
• 593-60-2 Vinyl bromide 
• 766-97-2 4-n-methylphenylacetylene 
• 87639-41-6 4-p-tolylbut-3-yn-1-yl triflate 
• 31208-53-4 4-p-tolylbut-3-yn-1-ol 
• 75-89-8 2,2,2-trifluoroethanol 

Downstream Products

• 85157-61-5 1‐(2‐cyclopropylethynyl)‐4‐methylbenzene 

Relevant articles and documents

Stereodivergent Synthesis of Tertiary Fluoride-Tethered Allenes via Copper and Palladium Dual Catalysis

Herein we describe a protocol for the unprecedented stereodivergent synthesis of tertiary fluoride-tethered allenes bearing a stereogenic center and stereogenic axis via Cu/Pd synergistic catalysis. A broad scope of conjugated enynes are coupled with various α-fluoroesters in high yields with high diastereoselectivities and generally >99% ee. In addition, the four stereoisomers of the allene products ensure precise access to the corresponding four stereoisomers of the fluorinated hydrofurans via a novel stereodivergent axial-to-central chirality transfer process.

Fe-Catalyzed Selective Cyclopropanation of Enynes under Photochemical or Thermal Conditions

The nucleophilic Fe-complex Bu4N[Fe(CO)3(NO)] (TBA[Fe]) catalyzes the cyclopropanation of enynes to substituted propargyl cyclopropanes using diazoesters as carbene surrogates. The catalyst can be activated either thermally in the presence of catalytic amounts of 4-nitroanisole or under photochemical conditions. Cyclopropanation occurs selectively at the enyne moiety; alternative olefinic moieties remain intact.

Triple-Bond Insertion Triggers Highly Regioselective 1,4-Aminomethylamination of 1,3-Enynes with Aminals Enabled by Pd-Catalyzed C-N Bond Activation

A highly chemo- and regioselective 1,4-aminomethylamination of simple enynes with aminals to allenic 1,5-diamines by taking advantage of C-N bond activation has been reported. The reaction proceeds under mild reaction conditions and can be performed under