300343-75-3

Upstream product

• 100-39-0 benzyl bromide 

Downstream Products

• 300343-77-5 [(S)-2-Benzyloxy-3-((3aS,4R,5aS,9aR,11S,11aR)-2,2,11-trimethyl-decahydro-1,3,5,9-tetraoxa-benzo[a]cyclopenta[e]cycloocten-4-yl)-propoxy]-tert-butyl-diphenyl-silane 
• 300343-79-7 (S)-2-Benzyloxy-3-((3aS,4R,5aS,9aR,11S,11aR)-2,2,11-trimethyl-decahydro-1,3,5,9-tetraoxa-benzo[a]cyclopenta[e]cycloocten-4-yl)-propan-1-ol 
• 300343-80-0 (S)-2-Benzyloxy-3-((3aS,4R,5aS,9aR,11S,11aR)-2,2,11-trimethyl-decahydro-1,3,5,9-tetraoxa-benzo[a]cyclopenta[e]cycloocten-4-yl)-propionaldehyde 
• 300343-81-1 (2S,4aR,5R,6S,7aR,11aS,12aR)-2-Benzyloxy-6-methyl-dodecahydro-4,8,12-trioxa-dibenzo[a,d]cyclooctene-3,5-diol 

Relevant academic research and scientific papers

Synthetic studies on the HIJK-ring fragment of ciguatoxin

Synthesis of the tetracyclic HIJK-ring fragment of ciguatoxin with high stereoselectivity has been achieved starting from a sugar derivative directed toward the synthesis of the right part of ciguatoxin. Sonogashira coupling of a vinyl iodide with an acetylene derivative, cobalt complex-mediated (seven- and eight-membered ring) cyclizations and a heteroconjugate addition reaction play important roles in the current research work. (C) 2000 Elsevier Science Ltd.