300362-75-8

Upstream product

• 74808-09-6 2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl trichloroacetimidate 
• 300362-70-3 3-(3,4-bis(benzyloxy)phenethylcarbamoyl) propanoic acid 
• 62-31-7 dopamine hydrochloride 
• 300362-80-5 N-tert-butoxycarbonyl-3,4-dibenzyloxyphenylethylamine 
• 37034-31-4 N-(tert-butoxycarbonyl)dopamine 

Relevant academic research and scientific papers

Synthesis and biological studies of glycosyl dopamine derivatives as potential antiparkinsonian agents

A new approach to deliver dopamine into the central nervous system, based on the use of D-glucose as transportable agent, has been studied. Glycosyl dopamine derivatives bearing the sugar moiety linked to either the amino group or the catechol ring of dopamine through amide, ester or glycosidic bonds were synthesised as potential antiparkinsonian agents. Studies on the binding to dopamine D2 receptor, in vitro stability, and locomotive effect in mice of the synthetic glycoconjugates are reported. Copyright (C) 2000 Elsevier Science Ltd.