300362-80-5

Usage

Uses

Used in Pharmaceutical Synthesis:
tert-butyl N-2-[3,4-bis(benzyloxy)phenyl]ethylcarbamate is used as an intermediate in the synthesis of S-(-)-Tretoquinol Hydrochloride (T798100), a selective β-2-adrenoreceptor agonist. tert-butyl N-2-[3,4-bis(benzyloxy)phenyl]ethylcarbamate is particularly effective in the treatment of obstructive airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD), due to its bronchodilatory properties.
Used in the Treatment of Obstructive Airway Diseases:
In the medical industry, tert-butyl N-2-[3,4-bis(benzyloxy)phenyl]ethylcarbamate is used as a precursor for the development of S-(-)-Tretoquinol, a bronchodilator. This medication helps to relax and widen the airways, improving airflow and reducing symptoms associated with obstructive airway diseases. tert-butyl N-2-[3,4-bis(benzyloxy)phenyl]ethylcarbamate's role in the synthesis of S-(-)-Tretoquinol makes it a valuable component in the development of new treatments for respiratory conditions.

Upstream product

• 51-61-6 dopamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 100-39-0 benzyl bromide 
• 62-31-7 dopamine hydrochloride 
• 37034-31-4 N-(tert-butoxycarbonyl)dopamine 

Downstream Products

• 1354541-54-0 C₂₆H₂₃NO₄ 
• 1301637-05-7 C₆₀H₉₁N₇O₁₃ 
• 300362-75-8 1-O-[N-(3,4-dibenzyloxyphenylethyl)-succinamyl]-2,3,4,6-tetra-O-benzyl-β-D-glucopyranose 
• 446302-69-8 N-[2-(3,4-Bis-benzyloxy-phenyl)-ethyl]-succinamic acid (2R,3R,4S,5R,6R)-6-benzyloxy-3,4,5-tris-trimethylsilanyloxy-tetrahydro-pyran-2-ylmethyl ester 
• 300362-72-5 benzyl 6-O-[N-(3,4-dibenzyloxyphenylethyl)succinamyl]-β-D-glucopyranoside 
• 760190-09-8 N-[2-(3,4-bis-benzyloxyphenyl)ethyl]succinimic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 816429-78-4 N-[2-(3,4-bis-benzyloxy-phenyl)-ethyl]-succinamic acid methyl ester 
• 300362-70-3 3-(3,4-bis(benzyloxy)phenethylcarbamoyl) propanoic acid 

Relevant academic research and scientific papers

Hybrid hydrogels derived from renewable resources as a smart stimuli responsive soft material for drug delivery applications

The design and synthesis of amphiphilic molecules play a crucial role in fabricating smart functional materials via self-assembly. Especially, biologically significant natural molecules and their structural analogues have inspired chemists and made a majo

Hexagonal magnetite nanoprisms: Preparation, characterization and cellular uptake

The capacity of iron oxide nanocrystals to heat tissue when subjected to an alternating magnetic field (AMF hyperthermia) is shape-selective. Although iron oxide nanostructures with numerous shapes have been synthesized to date, hexagonal Fe3O

Bifunctional catechol based linkers for modification of TiO2 surfaces

Bifunctional linkers for modification of TiO2 nanoparticles were prepared containing a catechol group for TiO2 surface attachment and a maleimide and alkyne group for Michael addition and Cu catalysed Huisgen cycloaddition respectively. Peptide and fluorophore functionalised TiO 2 NPs were prepared, different purification methodologies were explored and conjugates were characterized using a range of methods.

Metal-assisted assembly and stabilization of collagen-like triple helices

Single-chain and TRIS-assembled collagen mimetic peptide structures incorporating catechol groups were synthesized. When 1/3 equiv of Fe3+ was added to the single-chain compound in 50 mM CAPS buffer (pH 10), the 1:3 Fe3+-catechol complex that formed acted as an N-terminal scaffold to assemble the triple helix. When 1 equiv of Fe3+ was added to the TRIS-assembled compound in the buffer solution, the Fe3+-catechol complex acted as an extra C-terminal scaffold, which lead to a triple helix with both termini tethered. The formation of this C-terminal complex increased the Tm by a remarkable 22 °C! Copyright

Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles

We report on the use of dopamine (DA) as a robust molecular anchor to link functional molecules to the iron oxide shell of magnetic nanoparticles. Using nitrilotriacetic acid (NTA) as the functional molecule, we created a system with an M/Fe2O

Synthesis and biological studies of glycosyl dopamine derivatives as potential antiparkinsonian agents

A new approach to deliver dopamine into the central nervous system, based on the use of D-glucose as transportable agent, has been studied. Glycosyl dopamine derivatives bearing the sugar moiety linked to either the amino group or the catechol ring of dopamine through amide, ester or glycosidic bonds were synthesised as potential antiparkinsonian agents. Studies on the binding to dopamine D2 receptor, in vitro stability, and locomotive effect in mice of the synthetic glycoconjugates are reported. Copyright (C) 2000 Elsevier Science Ltd.