30044-78-1

Basic information

• Product Name: pseudocoptisine chloride
• CAS NO: 30044-78-1
• Molecular Weight: 355.777
• Mol File: 30044-78-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: pseudocoptisine chloride(CAS DataBase Reference)
• NIST Chemistry Reference: pseudocoptisine chloride(30044-78-1)
• EPA Substance Registry System: pseudocoptisine chloride(30044-78-1)

Safety Data

• Hazardous Substances Data: 30044-78-1(Hazardous Substances Data)

Upstream product

• 131543-46-9 Glyoxal 
• 355816-19-2 N-[3,4-(methylenedioxy)benzyl]-3,4-(methylenedioxy)phenethylamine 
• 1653-64-1 homopiperonylamine hydrochloride 
• 1485-00-3 5-(2-nitrovinyl)benzo[1,3]dioxole 
• 2139-43-7 5-bromo-6-(1,3-dioxolan-2-yl)benzo[d][1,3]dioxolane 
• 855391-64-9 (2-Benzo[1,3]dioxol-5-yl-ethyl)-[1-benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-amine 
• 120-57-0 piperonal 
• 1484-85-1 3,4-methylenedioxyphenylethylamine 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 6006-82-2 3,4-methylenedioxyphenethyl alcohol 
• 2861-28-1 1,3-benzodioxole-5-acetic acid 

Relevant articles and documents

Berberine derivatives, preparation method thereof and application of berberine derivatives as p300 HAT small molecule inhibitor

The invention discloses berberine derivatives, a preparation method thereof and an application of the berberine derivatives as a p300 HAT small molecule inhibitor, and belongs to the technical field of medicinal chemistry. An effective component berberine hydrochloride in a natural product coptis chinensis is taken as a research object and is subjected to structural modification and transformationso as to obtain a series of berberine hydrochloride derivatives. The berberine derivatives have the characteristics of high activity, high selectivity and high safety for p300 HAT, and solves the problems of high cytotoxicity, weak affinity, low activity and poor selectivity of existing p300 HAT small molecule inhibitors.

Derivatives Of Protoberberine Biological Alkaloids And Use Of Same Inhibiting Ulcerative Colitis

Disclosed are derivatives of protoberberine biological alkaloids or physiologically acceptable salts thereof produced by means of a derivative reaction of a source material of biological alkaline quaternary ammonium salts of protoberberine alkaloids, a preparation method for same and pharmaceutical uses thereof. The derivatives of protoberberine biological alkaloids or the physiologically acceptable salts thereof show activity inhibiting ulcerative colitis and can be used in the preparation of drugs for same.

DERIVATIVES OF PROTOBERBERINE BIOLOGICAL ALKALOIDS AND USE OF SAME INHIBITING ULCERATIVE COLITIS

Disclosed are derivatives of protoberberine biological alkaloids or physiologically acceptable salts thereof produced by means of a derivative reaction of a source material of biological alkaline quaternary ammonium salts of protoberberine alkaloids, a preparation method for same and pharmaceutical uses thereof. The derivatives of protoberberine biological alkaloids or the physiologically acceptable salts thereof show activity inhibiting ulcerative colitis and can be used in the preparation of drugs for same.