30048-94-3 Usage
Uses
Used in Pharmaceutical Research:
2-(TRIFLUOROMETHYL)NAPHTO-[2,3-D]-IMIDAZOLE is used as a key intermediate in the synthesis of biologically active molecules for pharmaceutical applications. Its unique structure and fluorinated nature make it a promising candidate for the development of new drugs, especially in the area of antifungal and antibacterial agents.
Used in Agrochemical Research:
In the agrochemical industry, 2-(TRIFLUOROMETHYL)NAPHTO-[2,3-D]-IMIDAZOLE is used as a building block for the creation of novel agrochemicals. Its potential as an antifungal and antibacterial agent makes it a valuable component in the development of new pesticides and other agricultural chemicals aimed at protecting crops and enhancing yield.
Used in Medicinal Chemistry:
2-(TRIFLUOROMETHYL)NAPHTO-[2,3-D]-IMIDAZOLE is employed as a structural component in the design and synthesis of new medicinal compounds. Its presence in a molecule can influence the compound's pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, which are crucial for drug efficacy and safety.
Used in Agricultural Chemistry:
In agricultural chemistry, 2-(TRIFLUOROMETHYL)NAPHTO-[2,3-D]-IMIDAZOLE is used as a component in the development of new agrochemicals with improved properties. Its potential as an antifungal and antibacterial agent can lead to the creation of more effective and environmentally friendly pesticides and other agricultural products.
Check Digit Verification of cas no
The CAS Registry Mumber 30048-94-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,0,4 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 30048-94:
(7*3)+(6*0)+(5*0)+(4*4)+(3*8)+(2*9)+(1*4)=83
83 % 10 = 3
So 30048-94-3 is a valid CAS Registry Number.
30048-94-3Relevant academic research and scientific papers
Fe(OTf)3-catalyzed practical synthesis of 2-trifluoromethylarylimidazoles from o-arylenediamines and hexafluoroacetylacetone
Zhou, Yanmei,Shen, Guanshuo,Sui, Yuebo,Zhou, Haifeng
supporting information, p. 3396 - 3399 (2016/07/11)
An iron-catalyzed practical synthesis of 2-trifluoromethylarylimidazoles through condensation of o-arylenediamines and hexafluoroacetylacetone followed by intramolecular addition and C–C bond cleavage in one-pot has been developed. A series of title compounds were obtained with up to 99% yield. This method is quite practical and suitable for scalable preparation due to simple experimental procedure and readily available reagents.
Efficient syntheses of 2-fluoroalkylbenzimidazoles and -benzothiazoles
René, Olivier,Souverneva, Alexandra,Magnuson, Steven R.,Fauber, Benjamin P.
supporting information, p. 201 - 204 (2013/02/22)
We report an efficient one-step route to 2-fluoroalkylbenzimidazoles and -benzothiazoles via the condensation of fluorinated carboxylic acids and aromatic diamines or aminothiophenols. Additionally, we describe the syntheses of fluoroalkyl-azabenzimidazoles, -purines, and -imidazolopyrazines. This method is high-yielding with broad scope and is operationally simple with potential application to parallel synthesis.
